China Medical System: New Drug Application for Vitiligo Indication of Ruxolitinib Phosphate Cream Accepted in China ACN Newswire

China Medical System: New Drug Application for Vitiligo Indication of Ruxolitinib Phosphate Cream Accepted in China

SHENZHEN, Sept 24, 2024 - (ACN Newswire via SeaPRwire.com) - China Medical System Holdings Limited (the “Company”, together with its subsidiaries, the “Group” or “CMS”) is pleased to announce that on September 24, 2024, the New Drug Application (NDA) for vitiligo indication of ruxolitinib phosphate cream (the “ruxolitinib cream” or the “Product”) has been accepted by the National Medical Products Administration of China (NMPA). This is another substantial milestone for ruxolitinib cream in China, following the approval for Urgent Clinical Import by Hainan Medical Products Administration and approval for marketing in Macau for vitiligo, and it is also a key step in benefiting over ten million of patients with vitiligo in China.Ruxolitinib cream achieved positive results in Chinese Real-World Study. The primary efficacy endpoint was the proportion of patients in the treatment group who achieved F-VASI 75 response at week 24, which was 49.5%, significantly higher than the target value of 14.1% (p
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HKTDC Export Confidence Index 3Q24: Positive exporter confidence amid solid sales ACN Newswire

HKTDC Export Confidence Index 3Q24: Positive exporter confidence amid solid sales

HONG KONG, Sept 24, 2024 - (ACN Newswire via SeaPRwire.com) – Hong Kong traders remain optimistic about their prospects with a sustained period of moderate growth believed to be underway. This was the key finding of the Hong Kong Trade Development Council (HKTDC) Export Confidence Index for the third quarter of 2024 as released today.The Index – a quarterly review of the views and expectations of Hong Kong-based traders across a broad cross-section of industry sectors – showed that, despite a slight decline compared to the second quarter, underlying sentiment remains broadly positive. In another welcome outcome, the majority of the sub-indices remained in expansionary territory, a clear indication of widespread anticipation of continued growth.Putting the overall findings into context, Irina Fan, Director of HKTDC Research, said: “Hong Kong exporters remain resilient, despite the uncertainty stemming from lingering trade tensions. Indeed, the majority of respondents reported no – or only minimal – impact from the recent round of trade restrictions and higher tariffs.”Strong sales and new ordersLooking at the findings in greater detail, the overall Current Performance Index rose by 1 point to 52.6, a development seen as reflecting strong sales and new orders, rising unit prices and expanding procurement activities. This was underlined by concurrent rises in the relevant Sub-Indices – the Trade Value Sub-Index (56.2, +2.5) and Procurement Sub-Index (57.3, +3.3). Although the Sales & New Orders Sub-Index recorded a moderate 1.8-point drop, it stayed resolutely in expansionary territory at 55.7.The Expectation Index also remained in expansionary territory at 51.4 even after a 2.9-point dip. This decrease was driven mainly by the 8.5-point decline in the Trade Value Expectation Sub-Index (down to 51.7), with traders expecting unit prices to increase only moderately.The same traders, however, remained optimistic about the outlook for sales and new orders (with a Sales & New Orders Expectation Sub-Index reading of 54.6); and look set to continue to expand their procurement activities (Procurement Expectation Sub-Index: 55.4).Overall, the findings suggest that the immediate future will be characterised by moderate, sustained export growth.Cost pressures lessen, but remain major concernIt was also apparent that costs remained the major drag on exporter confidence in the third quarter. While both the Current and Expectation Cost Sub-Index showed some improvement, scores remained at about the 35 level, an indication that exporters are still facing strong cost pressures.In terms of Current Performance, exporters have seen increased Sales and New Orders across all their key markets. With regard to outlook (Expectation), exporters were most upbeat about the ASEAN bloc (59.7) and mainland China (58.4).By industry, the third quarter saw an improvement in Current Performance across all sectors. In terms of prospects for the near-term, Clothing exporters are the most optimistic at 61.2, followed by Toys (58.7) and Jewellery (56.4).Looking to the immediate future, Nicholas Fu, Senior Economist with HKTDC Research, said: “Exporters from five out of the six key sectors expect the current positive business momentum to continue. Overall, Clothing exporters were the most upbeat, followed by those in the Toys and Jewellery sectors. While it is noteworthy that cost pressures are expected to stay high across all sectors, there is some possibility of a slight improvement further down the line.”In addition to addressing the standard index criteria, the latest survey also focused on several specific thematic questions with regard to the primary challenges facing exporters and the favoured forward strategies of participants. Responses here showed that:- High and rising costs (transport, labour, production and capital) were seen as the most significant challenges.- In order to mitigate any related risks, Hong Kong exporters intend to adopt more cautionary business strategies.- Regarding the impact of recent trade restrictions and higher tariffs on certain China-origin exports, 60% of respondents reported no impact on their business to date, while 39% expect only a moderate downside.- On the sustainability front, however, fewer than 20% of respondents were familiar with the EU's newly enacted Ecodesign for Sustainable Products Regulations (ESPR), which is expected to have a broad impact across many industry sectors.Notes for EditorsThe HKTDC Export Confidence Index was introduced in the first quarter of 2024. It is a composite of five sub-indices – Sales and New Orders, Trade Value, Cost, Procurement and Inventory – and seeks to provide a comprehensive overview of Hong Kong exporter sentiment.There are two primary / overall indices, one of which gauges the Current Performance in the present quarter, while the other considers the Expectation for the upcoming quarter via a weighted average of the following five sub-indices:- Sales and New Orders: This is an indication of overall export performance as well as the level of new export orders received by respondents. This index is compiled based on respondents' feedback regarding the prospects of each of their major export markets.- Trade Value: This focuses on tracking the movement of unit export prices.- Cost: This tracks cost pressures as they relate to day-to-day operations, including raw material prices / labour and other operational costs/ financing requirements. Compared with the other indices, it is an inverted index, with an index reading above 50 indicating a downward trend for costs, while a reading below 50 indicates an upward trend for costs.- Procurement: This is a measure of the input-buying activity of Hong Kong traders.- Inventory: This tracks the overall inventory levels held by respondents for present use and the upcoming quarter. An index reading above 50 indicates a lower-than-normal inventory level, while a reading below 50 indicates a higher-than-normal inventory level.To view this press release in Chinese, please visit http://mediaroom.hktdc.com/tcReferences- HKTDC Research website: http://research.hktdc.com/- HKTDC Export Confidence Index 3Q24: Sustained Optimism Underpinned by Strong Sales and New Orders https://research.hktdc.com/en/article/MTgwNDk1NTM5OQPhoto download: https://bit.ly/4deCzLZHKTDC Director of Research Irina Fan (left) and Senior Economist Nicholas Fu (right) announced the HKTDC Export Confidence Index for the third quarter of 2024 at a press conference todayHKTDC Director of Research Irina FanHKTDC Senior Economist Nicholas FuMedia enquiriesPlease contact the HKTDC’s Communication and Public Affairs Department:Jane CheungTel: (852) 2584 4137Email: jane.mh.cheung@hktdc.orgAbout HKTDCThe Hong Kong Trade Development Council (HKTDC) is a statutory body established in 1966 to promote, assist and develop Hong Kong's trade. With 50 offices globally, including 13 in Mainland China, the HKTDC promotes Hong Kong as a two-way global investment and business hub. The HKTDC organises international exhibitions, conferences and business missions to create business opportunities for companies, particularly small and medium-sized enterprises (SMEs), in the mainland and international markets. The HKTDC also provides up-to-date market insights and product information via research reports and digital news channels. For more information, please visit: www.hktdc.com/aboutus. Copyright 2024 ACN Newswire via SeaPRwire.com.
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Zelenskyy memberi amaran pelan Vance untuk menyerahkan tanah yang dirampas Rusia akan membawa kepada ‘pertembungan global’ Berita

Zelenskyy memberi amaran pelan Vance untuk menyerahkan tanah yang dirampas Rusia akan membawa kepada ‘pertembungan global’

(SeaPRwire) - Dalam temu bual pada hujung minggu dengan The New Yorker, Zelenskyy menyuarakan beberapa kritikan terkasarnya terhadap mana-mana pegawai AS sejak perang Rusia bermula ketika ditekan mengenai calon naib presiden Republikan Senator JD Vance.Zelenskyy secara jelas telah mematuhi garis apabila tiba masanya untuk pilihan raya presiden AS 2024 yang penuh kontroversi dan telah bercakap dengan setiap Presiden Biden, calon presiden Demokrat Naib Presiden Harris dan calon GOP bekas Presiden Trump.Tetapi sarung tangan ditanggalkan pada hari Ahad dalam satu temu bual di mana Zelenskyy memanggil Vance "radikal" dan memberi amaran bahawa cadangannya untuk menamatkan perang di Ukraine sebaliknya akan mendorong "pertembungan global."Vance berkata pada bulan ini bahawa jika terpilih sebagai Presiden, Trump akan bekerjasama dengan Rusia, Ukraine dan pemimpin Eropah untuk membuat perjanjian yang akan memberi Moscow wilayah yang telah dirampasnya secara haram sejak pencerobohan 2022.Setelah persetujuan Kyiv untuk memberikan tanah itu kepada Rusia, maka akan ada penciptaan zon demiliterisasi di sepanjang garis hadapan semasa, Ukraine akan diperkukuh untuk menghalang pencerobohan Rusia yang ketiga, dan Kyiv akan bersetuju untuk melupakan rancangannya untuk menyertai NATO - satu cadangan yang telah dikatakan oleh pakar keselamatan Barat akan menjadi kekalahan besar."Jika ini adalah pelan, maka Amerika menuju ke arah konflik global," kata Zelenskyy. "Ia akan bermakna bahawa sesiapa sahaja yang mendakwa memiliki wilayah - bukan pemilik yang sah tetapi sesiapa sahaja yang datang sebulan atau seminggu yang lalu dengan pistol di tangan - adalah orang yang bertanggungjawab."Presiden Ukraine memberi amaran bahawa sikap ini bukan sahaja akan merugikan Kyiv dan rakyat Ukraine, tetapi juga akan membahayakan tatanan dunia di mana-mana, termasuk di Timur Tengah dan di mana-mana sahaja China mengancam kepentingan Barat."Kita akan berakhir dalam dunia di mana kekuatan adalah hak," kata Zelenskyy. "Ia akan menjadi dunia yang sama sekali berbeza, pertembungan global."Walaupun kritiknya terhadap Vance, Zelenskyy cuba menekankan bahawa dia telah mengalami pengalaman yang berbeza dalam urusannya dengan calon ketua Republikan untuk presiden."Saya harus mengatakan bahawa tidak begitu dengan Trump. Dia dan saya bercakap melalui telefon, dan pesannya sepositif yang boleh dari sudut pandangan saya," kata Zelenskyy kepada The New Yorker, menguraikan pujian yang dikeluarkan oleh Trump seperti "Saya faham" dan "Saya akan memberi sokongan."Trump telah mendapat kritikan kerana gagal untuk memperincikan apa yang akan dilakukan oleh pentadbirannya dalam membantu Ukraine, walaupun dia telah secara lantang mengkritik jumlah bantuan yang telah diberikan Washington kepada Kyiv.Bekas presiden itu berkata bahawa jika terpilih, dia akan menamatkan perang antara Ukraine dan Rusia sebelum mengambil jawatan tertinggi pada Januari 2025, walaupun dia tidak menjelaskan bagaimana dia akan melakukan ini."Trump membuat kenyataan politik dalam kempen pilihan rayanya," kata Zelenskyy. "Perasaan saya ialah Trump tidak benar-benar tahu cara menghentikan perang, walaupun dia mungkin berfikir bahawa dia tahu caranya.""Dengan perang ini, sering kali semakin dalam anda melihatnya, semakin kurang anda faham," tambah Zelenskyy.Zelenskyy, yang berada di AS untuk menghadiri Perhimpunan Agung Pertubuhan Bangsa-Bangsa Bersatu, berkata dia akan bertemu dengan Biden untuk membentangkan "pelan kemenangan" yang bertujuan untuk menyatukan sekutu Barat lebih lanjut menentang Rusia dan mengamankan Ukraine kepada tahap yang lebih besar.Presiden Ukraine tidak memperincikan apa yang terdapat dalam pelan itu, walaupun ia dijangka termasuk seruan untuk bantuan ketenteraan tambahan dan jaminan keselamatan, walaupun ia juga boleh termasuk rancangan untuk mempercepatkan kemasukan Kyiv ke dalam EU dan perikatan lain yang seumpamanya."Ukraine yang kuat akan memaksa Putin untuk berunding. Saya yakin tentang itu," kata Zelenskyy.Terdapat kebimbangan bahawa Biden boleh menolak seruan untuk lebih banyak bantuan AS kepada Ukraine dengan pilihan raya presiden hanya lebih dari sebulan setengah lagi."Itu adalah pemikiran yang mengerikan. Ia akan bermakna bahawa Biden tidak mahu menamatkan perang dengan cara yang menafikan kemenangan kepada Rusia. Dan kita akan berakhir dengan perang yang sangat lama, keadaan yang mustahil dan meletihkan yang akan membunuh sejumlah besar orang," tambahnya.Tetapi Zelenskyy juga berkata Ukraine sudah biasa "hidup dalam Pelan B" dan dia tidak "menyalahkan" Biden atas bagaimana perang itu berlaku."Pada akhirnya, dia mengambil langkah yang berkuasa dan bersejarah ketika dia memilih untuk menyokong kami pada permulaan perang, tindakan yang mendorong rakan kongsi lain kami untuk melakukan perkara yang sama," tambahnya.Walaupun Zelenskyy juga memberi amaran bahawa keamanan hanya boleh dicapai jika Kyiv diberikan apa yang diperlukan untuk berada dalam kedudukan untuk berunding dengan Moscow dengan sewajarnya."Jika anda tidak mahu perang ini berlarutan, jika anda tidak mahu Putin menguburkan kami di bawah mayat rakyatnya, mengambil lebih banyak nyawa Ukraine dalam proses itu, kami menawarkan anda pelan untuk mengukuhkan Ukraine," katanya. "Ia bukan fantasi dan bukan fiksyen sains, dan yang penting, ia tidak memerlukan Rusia untuk bekerjasama untuk berjaya."Pelan itu menyatakan apa yang boleh dilakukan oleh rakan kongsi kita tanpa penyertaan Rusia. Jika diplomasi adalah keinginan kedua-dua pihak, maka sebelum diplomasi boleh berkesan, pelaksanaan pelan kita hanya bergantung kepada kita dan rakan kongsi kita," tambah Zelenskyy.Kempen Vance tidak membalas permintaan untuk komen daripada Axios Digital.Artikel ini disediakan oleh pembekal kandungan pihak ketiga. SeaPRwire (https://www.seaprwire.com/) tidak memberi sebarang waranti atau perwakilan berkaitan dengannya. Sektor: Top Story, Berita Harian SeaPRwire menyampaikan edaran siaran akhbar secara masa nyata untuk syarikat dan institusi, mencapai lebih daripada 6,500 kedai media, 86,000 penyunting dan wartawan, dan 3.5 juta desktop profesional di seluruh 90 negara. SeaPRwire menyokong pengedaran siaran akhbar dalam bahasa Inggeris, Korea, Jepun, Arab, Cina Ringkas, Cina Tradisional, Vietnam, Thai, Indonesia, Melayu, Jerman, Rusia, Perancis, Sepanyol, Portugis dan bahasa-bahasa lain.
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Biden Akan Berucap di Perhimpunan Agung PBB Kali Terakhir Semasa Diktator dan Despot Datang ke New York Berita

Biden Akan Berucap di Perhimpunan Agung PBB Kali Terakhir Semasa Diktator dan Despot Datang ke New York

(SeaPRwire) - Presiden Biden dijangka menyampaikan ucapan di pada Selasa pagi ketika pemimpin dan wakil daripada 134 negara berbondong-bondong ke Bandaraya New York untuk konvensyen tersebut. Walaupun begitu, ketua-ketua negara beberapa negara autoritarian utama yang terlibat dalam konflik antarabangsa di seluruh dunia tidak akan hadir.Walaupun Presiden Rusia Vladimir Putin, Presiden China Xi Jinping dan pemimpin Korea Utara Kim Jong Un tidak akan hadir, Presiden Iran Masoud Pezeshkianis dijangka menyampaikan ucapan pada hari Selasa walaupun mendapat tentangan antarabangsa berikutan sokongan Tehran terhadap keganasan, campur tangan dalam pilihan raya AS November dan ancaman pembunuhan terhadap ahli politik Amerika, termasuk bekas Presiden Trump.Menurut laporan pada hari Isnin, Pezeshkian memberitahu wartawan dari New York, "Kami tidak mahu berperang … kami mahu hidup dalam keamanan."Tetapi komen beliau tidak dijangka diterima begitu sahaja, dan Biden, yang akan berucap sebelum presiden Iran, akan "mengumpulkan tindakan global untuk menangani cabaran paling mendesak di dunia," kata setiausaha akhbar Rumah Putih Karine Jean-Pierre pada hari Isnin.Biden dijangka menggariskan keutamaan pentadbirannya dan visi untuk badan antarabangsa itu dalam ucapan terakhirnya kepada PBB sebagai presiden.Menurut Linda Thomas-Greenfield, Washington mempunyai tiga bidang tumpuan utama yang akan ditekankan semasa acara minggu ini, termasuk usaha berterusan untuk "menamatkan wabak perang" kerana kira-kira suku penduduk dunia tinggal di "kawasan yang terjejas konflik" di tengah-tengah perang yang semakin meningkat.AS juga merancang untuk mendorong negara anggota lain untuk meningkatkan sokongan mereka kepada pekerja bantuan kemanusiaan sambil berusaha mewujudkan sistem antarabangsa yang lebih "inklusif dan berkesan" dengan menambah dua kerusi tetap baru di Majlis Keselamatan PBB (UNSC) untuk negara-negara Afrika serta satu lagi kerusi berputar yang dikhaskan untuk Negara-negara Berkembang Kepulauan Kecil.Tetapi ketika pentadbiran Biden bergerak untuk mengubah keadaan dalam badan antarabangsa itu, sementara beberapa , seorang pakar PBB menyatakan kebimbangannya bahawa PBB sedang mengelakkan ancaman hari ini dengan mengadakan mesyuarat yang memberi tumpuan kepada kebimbangan samar hari esok."Saya berharap [ada] 'Sidang Kemuncak Masa Kini' dan bukan 'Sidang Kemuncak Masa Depan', kerana masa depan memberi kita peluang untuk menjadi samar," kata Hugh Dugan, yang bertugas sebagai delegasi AS ke Pertubuhan Bangsa-Bangsa Bersatu dan sebagai penasihat kanan kepada 11 duta besar AS ke PBB antara 1989 dan 2015, kepada Digital merujuk kepada acara "Sidang Kemuncak Masa Depan" yang diadakan pada hujung minggu."Banyak hiperbola akan didengar minggu ini," tambahnya. "Jika ia 'Sidang Kemuncak Masa Kini', itu bermakna kebertanggungjawaban sekarang, sama ada kita berkesan sekarang dan sama ada PBB cekap."Walaupun seruan Thomas-Greenfield untuk "harapan" semasa ucapannya pada hari Jumaat, terdapat rasa muram yang ketara menjelang sidang kemuncak itu kerana konflik antarabangsa yang besar berterusan tanpa pengakhiran yang jelas, termasuk perang Rusia di Ukraine, , pengambilalihan geng Haiti, dan perang saudara di Sudan dan Myanmar.Setiausaha Agung PBB Antonio Guterres memberitahu wartawan minggu lalu bahawa Sidang Kemuncak Masa Depan adalah cabaran yang diajukan kepada negara-negara tahun lepas untuk bersiap sedia dan "dilahirkan daripada kenyataan pahit: Cabaran antarabangsa bergerak lebih cepat daripada kemampuan kita untuk menyelesaikannya."Guterres menyerlahkan "perpecahan geopolitik yang tidak terkawal" dan konflik yang "tidak terkawal", perubahan iklim dan laluan ke hadapan yang tidak jelas tentang cara untuk mengatasi kecerdasan buatan, yang merupakan isu besar yang telah mengenai cara untuk membangunkan dan menggunakannya merentasi pelbagai sektor, termasuk integrasi ketenteraan."Institusi dan rangka kerja global hari ini sama sekali tidak mencukupi untuk menangani cabaran yang kompleks dan bahkan eksistensial ini," katanya. "Dan bukan sesuatu yang mengejutkan. Institusi-institusi itu dilahirkan dalam zaman dahulu kala untuk dunia dahulu kala."Kita tidak dapat mewujudkan masa depan yang sesuai untuk cucu kita dengan sistem yang dibina untuk datuk nenek kita," amarannya dengan nada yang dijangka akan berlaku sepanjang sidang kemuncak itu.Tetapi Dugan sekali lagi menunjuk kepada isu kebertanggungjawaban, dan dia mempersoalkan sama ada lebih mudah bagi pegawai tertinggi PBB untuk mendesak perubahan besar dalam PBB daripada menilai sebarang salah urus wang, birokrasi dan politik dalaman dalam PBB.Walaupun 134 negara akan menghadiri acara tahun ini, ketua dua daripada lima kerusi tetap UNSC akan tidak hadir kerana Xi dari China dan Putin dari Rusia telah menghantar delegasi sebagai ganti, satu tindakan yang semakin biasa dalam beberapa tahun kebelakangan ini.Dugan, yang bertugas di Majlis Keselamatan Negara semasa pentadbiran Trump di mana dia menangani organisasi antarabangsa, berkata amalan ini membolehkan pemimpin autoritarian mengelakkan keperluan untuk menjawab soalan-soalan sukar yang kebanyakannya berasal dari negara-negara Barat dan sekutu serantau mereka, tetapi ia juga menunjukkan bahawa mereka "tidak peduli untuk menunjukkan rasa tidak hormat."Ketika ditanya mengenai dan kesahihannya, khususnya Majlis Keselamatan PBB, yang telah menjadi sangat terpecah antara AS, Britain dan Perancis berbanding Rusia dan China selepas pencerobohan Putin ke atas Ukraine, Dugan berkata dia percaya Majlis Keselamatan PBB terus memegang kedudukan penting dalam masyarakat global."Saya sentiasa berpendapat bahawa ia memang sah," katanya. "Mudah bagi kita untuk berkata, baiklah, ia tidak dapat mencapai konsensus, atau ia tidak mencapai dan, oleh itu, berkata ia tidak sah. Saya tidak percaya itu benar."Ujian sebenar keupayaannya ialah kemampuannya untuk terus mengumpulkan orang di sekeliling meja," Dugan meneruskan. "Walaupun ketua negara tidak berada di meja itu, delegasi tahu bahawa terlalu berbahaya untuk tidak berada di meja itu."Artikel ini disediakan oleh pembekal kandungan pihak ketiga. SeaPRwire (https://www.seaprwire.com/) tidak memberi sebarang waranti atau perwakilan berkaitan dengannya. Sektor: Top Story, Berita Harian SeaPRwire menyampaikan edaran siaran akhbar secara masa nyata untuk syarikat dan institusi, mencapai lebih daripada 6,500 kedai media, 86,000 penyunting dan wartawan, dan 3.5 juta desktop profesional di seluruh 90 negara. SeaPRwire menyokong pengedaran siaran akhbar dalam bahasa Inggeris, Korea, Jepun, Arab, Cina Ringkas, Cina Tradisional, Vietnam, Thai, Indonesia, Melayu, Jerman, Rusia, Perancis, Sepanyol, Portugis dan bahasa-bahasa lain.
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Mazda to open new R&D office in Azabudai Hills in early summer 2025 JCN Newswire

Mazda to open new R&D office in Azabudai Hills in early summer 2025

TOKYO, Sept 24, 2024 - (JCN Newswire via SeaPRwire.com) - Mazda Motor Corporation will open a new R&D office in the cosmopolitan Azabudai Hills (Azabudai, Minato-ku, Tokyo) in early summer 2025, an area projected to see continuous development.Mazda has set out its 2030 VISION "to be a car-loving company that creates moving experiences through the 'joy of driving'" and aspires to an ideal where everyone connected to the Mazda brand feels mentally refreshed, physically invigorated, and optimistic about each day.As advanced technologies such as generative AI gain widespread use, it is crucial to continue innovating software technologies alongside traditional hardware to deliver vibrant, engaging experiences to our customers through their cars. The new R&D office is expected to house development facilities, particularly in software, demonstrating Mazda's goal to become a dynamic workplace of choice for software engineers. It will also function as a hub for collaborative innovation, fostering partnerships with universities, companies, and research institutions in the Tokyo metropolitan area.Based on the belief that our people are our most valuable resource, Mazda is promoting initiatives, like this new R&D office, to maximize the contributions of its personnel, including corporate culture reforms, improvements to HR systems, and the establishment of value-creation platforms.In our aspiration to create a comfortable working environment, the new R&D office will feature an open workspace and be equipped with the latest technology. Further details regarding the specific floor area and facilities will be announced in due course.Azabudai Hills, the location for Mazda's new R&D officeTrue to Mazda's "human-centered" philosophy and commitment to the pursuit of a comfortable and rewarding work environment, we endeavor to create an exemplary company where every employee feels the pride and energy to work with enthusiasm. Copyright 2024 JCN Newswire via SeaPRwire.com.
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Rozebalamin(R) for Injection 25 mg (Mecobalamin) Approved in Japan for Amyotrophic Lateral Sclerosis JCN Newswire

Rozebalamin(R) for Injection 25 mg (Mecobalamin) Approved in Japan for Amyotrophic Lateral Sclerosis

Eisai Co., Ltd. announced today that it has obtained manufacturing and marketing authorization approval for amyotrophic lateral sclerosis (ALS) treatment “Rozebalamin® for Injection 25 mg” (mecobalamin) in Japan as a treatment for slowing progression of functional impairment in amyotrophic lateral sclerosis. In May 2022, it received orphan drug designation, and a new drug application was submitted in January 2024, leading to this approval.This approval is based on the results of JETALS (The Japan Early-Stage Trial of Ultrahigh-Dose Methylcobalamin for ALS), multicenter, placebo-controlled, double-blind, randomized Phase III clinical trial in 130 patients with ALS, that was conducted as an investigator-initiated trial by a research team with Extraordinary Professor Ryuji Kaji (Principal Investigator), Tokushima University, and Professor Yuishin Izumi (Coordinating Investigator), the Department of Neurology, Tokushima University Graduate School of Biomedical Sciences, and Professor Satoshi Kuwabara (Coordinating Investigator), the Department of Neurology, Chiba University Graduate School of Medicine.In JETALS, the mecobalamin 50mg group showed a statistically significant slowing of progression compared to the placebo group in the change in total score from the end of the observation period to week 16 of the treatment period in the primary endpoint, the Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS-R) (slowing decline by approximately 43%, p=0.01).1 The adverse drug reaction incidence rates were 1.6% in the placebo group and 7.7% in the mecobalamin 50 mg group. Adverse reactions observed in the mecobalamin 50 mg group included constipation, injection site pain, fever, electrocardiogram QT prolongation and rash, each occurring in 1.5% of patients.2ALS is an intractable, progressive, neurodegenerative disease that results in severe muscle atrophy and weakness in the muscles due to motor neuron dysfunction. As the main cause of death is respiratory failure due to paralysis of the respiratory muscles, without the use of an artificial respirator, death occurs within approximately 2 to 5 years from the onset of the disease.3 The number of patients in Japan is estimated to be approximately 10,000. 3 Currently, there is no curative treatment established for ALS, and since there are only limited number of medicines approved in Japan and abroad, this is a disease with significant unmet medical needs.Eisai considers neurology a therapeutic area of focus. As a human healthcare company, Eisai is committed to further addressing the diverse needs of, and increasing the benefits of, patients and their families by providing Rozebalamin as a new treatment option for ALS patients.1. Product Outline1) Product nameRozebalamin® for Injection 25 mg2) Generic nameMecobalamin3) Indication for useSlowing progression of functional impairment in amyotrophic lateral sclerosis4) Dosage and administrationThe usual dose of mecobalamin in adults is 50 mg a day, twice a week, injected intramuscularly.About Rozebalamin (generic name: mecobalamin, development code: E0302)Mecobalamin is approved and marketed as Methycobal®, a 500 µg injection of mecobalamin indicated for the treatment of peripheral neuropathies and megaloblastic anemia caused by vitamin B12 deficiency. Methycobal is also approved as a tablet formulation (250 µg and 500 µg) as well as a fine granule formulation (0.1%) indicated for the treatment of peripheral neuropathies. While the mechanism of action of mecobalamin against amyotrophic lateral sclerosis (ALS) is not known, it has been suggested in non-clinical research that mecobalamin may have efficacy through a neuroprotective effect and regeneration of nerve axons. Since the 1990s, clinical research has been carried out on ultrahigh-dose mecobalamin in ALS by a study group on neurodegenerative disease, funded through the Ministry of Health, Labour and Welfare's Specified Disease Treatment Research Program. Short- and long-term trials of intramuscular injection of mecobalamin at 25 mg and 50 mg per day, which is respectively 50 and 100 times the approved dosage of Methycobal, suggested that ultrahigh-dose mecobalamin could have a clinical effect in ALS, and Eisai then conducted the Phase II/III clinical trial (Study 761) from 2006. Eisai submitted a new drug application for ultrahigh-dose mecobalamin as treatment for ALS in May 2015 but withdrew the application in March 2016 after the Pharmaceuticals and Medical Devices Agency (PMDA) indicated that additional clinical trials were necessary.After obtaining favorable results in the investigator-initiated Phase III trial JETALS, and following consultation with Tokushima University, Eisai submitted a new drug application for the treatment of ALS in Japan in January 2024, leading to this approval.About Japan Early-stage Trial of Ultrahigh-Dose Methylcobalamin for ALS (JETALS)The Japan Early-stage Trial of Ultrahigh-Dose Methylcobalamin for ALS (JETALS) is an investigator-initiated study conducted as a multicenter, placebo-controlled, double-blind, randomized Phase III clinical trial to verify the efficacy and safety of high-dose methylcobalamin (mecobalamin) in patients with amyotrophic lateral sclerosis (ALS).1Mecobalamin 50 mg or placebo was administered intramuscularly twice weekly for 16 weeks to 130 ALS patients who had suffered from ALS for less than one year, were classified as “definite”, “probable”, or “probable- laboratory supported” according to the Updated Awaji Criteria, had an ALS severity rating of grade 1 or 2, had a decrease of 1 or 2 points in the total score on the Revised ALS Functional Rating Scale-Revised (ALSFRS-R) 12 weeks prior to administration, and had a forced vital capacity (%FVC) of more than 60%.2The primary endpoint was the change in ALSFRS-R total score from the end of the observation period to week 16 of the treatment period. The change was -2.7 [95% confidence interval (CI): -3.9, -1.5] in the mecobalamin50 mg group and -4.6 [95% CI: -5.8, -3.4] in the placebo group, with a difference in change of 2.0 (95% CI: 0.4, 3.5; p=0.012), verifying the superiority of mecobalamin 50 mg over placebo.2 The adverse drug reaction incidence rate was 1.6% (1/64 cases) in the placebo group and 7.7% (5/65 cases) in the mecobalamin 50 mg group. Adverse drug reactions observed in the mecobalamin 50 mg group were constipation, injection site pain, fever, electrocardiogram QT prolongation, and rash, occurring in 1.5% (1/65 cases) each.2(1) Oki R, et al. Efficacy and safety of ultrahigh-dose methylcobalamin in early-stage amyotrophic lateral sclerosis a randomized clinical trial. JAMA Neurol. 2022;79(6):575-583.(2) Information stated in the package insert.(3) Japan Intractable Diseases Information Center, Amyotrophic lateral sclerosis (ALS), Designated intractable disease (2). https://www.nanbyou.or.jp/entry/52. Last accessed: September 2024. (Japanese only)Media Inquiries:Public Relations Department, Eisai Co., Ltd.+81-(0)3-3817-5120 Copyright 2024 JCN Newswire via SeaPRwire.com.
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Valuufy CEO to present at the UN Science Summit (SSUNGA79) JCN Newswire

Valuufy CEO to present at the UN Science Summit (SSUNGA79)

KYOTO, Japan, September 24, 2024 - (JCN Newswire via SeaPRwire.com) - Valuufy, a pioneering force in sustainability assessment, announces its CEO Kyle Barnes will present at the prestigious Science Summit at the United Nations General Assembly (SSUNGA79) on September 26 as part of a larger panel session on the important role of SMEs in global sustainability efforts. This marks the third consecutive year that the Value Model has been included in this global forum.Valuufy's presentation will showcase how SMEs can become a more powerful force in global sustainability efforts. The session, "Empowering SMEs: Blockchain & AI for Sustainable Stakeholder Value", will also demonstrate how the ValuuCompass enables businesses of all sizes to measure, understand, and enhance value creation across all stakeholder groups.This is the third time the Value Model (which evolved into the ValuuCompass) has been presented at the SSUNGA, reinforcing the global relevance and potential of the ValuuCompass in addressing complex sustainability challenges, and offering a potential outline for how a post-SDGs could function."The ValuuCompass aims to become a global standard for sustainability by 2030, and this platform allows us to get important feedback at one of the world’s most important sustainability-focused events. We're excited to explore how blockchain and AI can help smaller businesses navigate the complex world of sustainability and position themselves as leaders in the post-SDG era," shares Kyle Barnes, CEO of Valuufy."We are honored to introduce the ValuuCompass as a powerful tool for driving sustainable business practices, especially for SMEs at this year’s Science Summit for the United Nations General Assembly."The ValuuCompass was developed by the Value Research Center at Doshisha University and is a practical tool that helps organizations measure their impact on seven key stakeholders: the organization itself, shareholders, employees, customers, partners, society, and the planet.“We know that a post-SDG world needs to act for people, planet, and prosperity and Valuufy speaks to this imperative. Its participation in SSUNGA79 builds on the discussions from previous years' presentations, which introduced the Value Model and explored its role in creating a sustainable post-SDG future,” acknowledges Heather Young, SSUNGA Japan Co-Chair.This year's focus on empowering SMEs with blockchain and AI technologies demonstrates Valuufy's commitment to making sustainable practices accessible and impactful for businesses of all sizes, and will include speakers across academia and business to explore how best to integrate the collective actions of SMEs to ensure global sustainability success.The virtual session is scheduled for Thursday, September 26, 2024, from 16:00 to 18:00 JST. There is no cost to attend, but registration is required: https://sched.co/1l8mcAbout ValuufyValuufy seeks to transform how the world understands and acts on sustainability. Founded in 2024, Valuufy, Inc is a registered Japanese startup in Kyoto, Japan, born of 10 years’ academic value research at Doshisha University and the Value Research Center. Led by an international team with expertise in value research, sustainability strategies, innovative technologies, business development, and ESG assessments, Valuufy provides a suite of products and services to promote value creation activities across stakeholders for businesses of all sizes. Valuufy aims to set new standards in transparent, data-driven decision-making in the realm of sustainability and value creation. For more on Valuufy's products and services and its impact on shaping the future of sustainability strategies, visit www.valuufy.com.Press and Media enquiries:news@valuufy.comFollow us:linkedin.com/company/valuufy Copyright 2024 JCN Newswire via SeaPRwire.com.
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Anticancer Agent “Tasfygo(R) Tablets 35mg” (Tasurgratinib Succinate) Approved in Japan for Biliary Tract Cancer with FGFR2 Gene Fusions or Rearrangements JCN Newswire

Anticancer Agent “Tasfygo(R) Tablets 35mg” (Tasurgratinib Succinate) Approved in Japan for Biliary Tract Cancer with FGFR2 Gene Fusions or Rearrangements

TOKYO, Sept 24, 2024 - (JCN Newswire via SeaPRwire.com) - Anticancer Agent “Tasfygo(R) Tablets 35mg” (Tasurgratinib Succinate) Approved in Japan for Biliary Tract Cancer with FGFR2 Gene Fusions or RearrangementsEisai Co., Ltd. announced today that it has obtained manufacturing and marketing approval for fibroblast growth factor receptor (FGFR) selective tyrosine kinase inhibitor “TASFYGO® Tablets 35mg” (tasurgratinib succinate) in Japan for the treatment of patients with unresectable biliary tract cancer with FGFR2 gene fusions or rearrangements that progressed after cancer chemotherapy. In Japan, it has received orphan drug designation from the Ministry of Health, Labour and Welfare (MHLW), and the marketing authorization application was submitted in December 2023.This approval is based on data such as the results of a multicenter, open-label, single-arm clinical phase II trial (Study 201) conducted by Eisai in Japan and China. Study 201 enrolled 63 patients with unresectable advanced or metastatic cholangiocarcinoma with FGFR2 gene fusions or rearrangements previously treated with gemcitabine-based combination chemotherapy. The primary endpoint of this study was objective response rate (ORR), and secondary endpoints included safety.1 This study achieved its primary endpoint and exceeded a prespecified tumor response threshold (15%) with statistical significance: ORR of patients treated with TASFYGO was 30.2% (90% confidence interval (CI): 20.7-41.0) as assessed by independent imaging review. Treatment-emergent adverse events (incidence of 25% or more) observed in this study were hyperphosphataemia (81.0%), palmar-plantar erythrodysaesthesia syndrome (44.4%), diarrhoea (36.5%), aspartate aminotransferase increase (31.7%), alanine aminotransferase increase (28.6%) and stomatitis (25.4%).The estimated number of patients in Japan with biliary tract cancer is approximately 22,0002,3 with approximately 25% of the five-year relative survival rate,2 making it an intractable cancer with the second worst prognosis following pancreatic cancer. Since drug therapy options are limited in comparison with other cancers, it is a disease with significant unmet medical needs. FGFR2 gene fusions or rearrangements are observed in approximately 14% of intrahepatic cholangiocarcinoma, which accounts for 15-30% of biliary tract cancers.4 FGFR genetic aberrations such as the gene fusions are known to be deeply involved in the proliferation, survival and migration of cancer cells as well as tumor angiogenesis and drug resistance. As these genetic aberrations in FGFRs have been observed in various other types of cancers as well as biliary tract cancer, there is growing interest in FGFRs as a promising target for cancer therapy. TASFYGO is thought to show tumor growth inhibition by selectively inhibiting FGFR1, 2 and 3, and blocking those signals.5,6 In non-clinical studies, the antitumor activity of TASFYGO was confirmed in cells expressing the FGFR2-fusion genes, which were identified by the National Cancer Center Japan (Headquarters: Tokyo) through large-scale genomic analysis of Japanese biliary tract cancer. The companion diagnostic test to detect FGFR2 gene fusions or rearrangements for the use of TASFYGO in biliary tract cancer, “AmoyDx® FGFR2 Break-apart FISH Probe Kit” by Nihon Stery, Inc. (Headquarters: Tokyo) was approved in August 2024.7Eisai aims to make continuous efforts to meet the diversified needs of and increase the benefits provided to patients with cancer, their families, and healthcare professionals, by delivering TASFYGO as a new treatment option for biliary tract cancer with FGFR2 gene fusions or rearrangements.1. Product Information1) Brand nameTASFYGO® Tablets 35mg2) Generic nameTasurgratinib succinate3) IndicationsUnresectable biliary tract cancer with FGFR2 gene fusions or rearrangements that progressed after cancer chemotherapy4) Dosage and AdministrationThe usual adult dose of tasurgratinib is 140mg orally once daily under fasting conditions. The dose may be reduced appropriately according to the condition of the patient.About “TASFYGO® Tablets 35mg” (tasurgratinib succinate, Development Code: E7090) Discovered in-house by Eisai’s Tsukuba Research Laboratories, TASFYGO is an orally available novel tyrosine kinase inhibitor that demonstrates selective inhibitory activity against fibroblast growth factor receptors (FGFR) FGFR1, FGFR2 and FGFR3. Distinct from prior known FGFR inhibitors, TASFYGO has a basic structure which lacks the dimethoxyphenyl moiety, and in a kinetic interaction analysis study, it was observed that TASFYGO demonstrates antitumor activities due to inhibition of kinase activity with a binding mode (Type V) that exhibits rapid and potent binding as well as high selectivity to FGFR. 5,6In non-clinical studies for biliary tract cancer, NIH/3T3 cells expressing FGFR2-AHCYL1, FGFR2-KCTD1, FGFR2-BICC1 or FGFR2-TXLNA as FGFR2-fusion genes, provided by the National Cancer Center Japan, were used. The antitumor activity of TASFYGO against FGFR2 gene fusion-positive cancers was confirmed in these models by evaluating its effect on anchorage-independent growth and subcutaneously transplanted tumor growth in mice.6A Phase I clinical trial is underway in Japan in patients with estrogen receptor-positive and HER2-negative breast cancer.(1) Furuse J. et al. Pivotal single-arm, phase 2 trial of tasurgratinib for patients with fibroblast growth factor receptor (FGFR)-2 gene fusion-positive cholangiocarcinoma (CCA). 2024 ASCO Gastrointestinal Cancers Symposium; Abstract No. 471. https://ascopubs.org/doi/pdf/10.1200/JCO.2024.42.3_suppl.471(2) Latest statistics, Cancer Information Service, National Cancer Center, Japan. (Japanese only)(3) The 23rd Follow-up Survey Reports for Primary Liver Cancer Cases in Japan (2014-2015), 2023. (Japanese only)(4) Arai Y. et al., Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma, Hepatology, 2014, 59, 1427-1434.(5) Miyano SW. et al., E7090, a Novel Selective Inhibitor of Fibroblast Growth Factor Receptors, Displays Potent Antitumor Activity and Prolongs Survival in Preclinical Models, Molecular Cancer Therapeutics, 2016, 15, 2630-2639.(6) Kawano S. et al., Antitumor Activity of Tasurgratinib as an Orally Available FGFR1-3 Inhibitor in Cholangiocarcinoma Models With FGFR2-fusion, Anticancer Research, 2024, 44, 2393-2406.(7) AmoyDx® FGFR2 Break-apart FISH Probe Kit Approved as Companion Diagnostic for Eisai’s Tasurgratinib in Japan. Available at: https://www.amoydiagnostics.com/about/press-releases/245 Last accessed: September 2024.Media Inquiries:Public Relations DepartmentEisai Co., Ltd.+81-(0)3-3817-5120 Copyright 2024 JCN Newswire via SeaPRwire.com.
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Autobrains Unveils Air2Road: Cutting-Edge Localization Technology for Automated Driving ACN Newswire

Autobrains Unveils Air2Road: Cutting-Edge Localization Technology for Automated Driving

MUNICH, GERMANY & TEL AVIV, ISRAEL, Sept 24, 2024 - (ACN Newswire via SeaPRwire.com) - Autobrains, a global leader in AI-powered automotive solutions, is pleased to unveil its latest innovation: Air2Road, a breakthrough localization technology developed to enhance the capabilities of Advanced Driver Assistance Systems (ADAS) and Autonomous Driving solutions. Powered by Autobrains' Liquid AI Technology, Air2Road delivers precise, real-time vehicle localization for safe and efficient navigation, even in challenging conditions such as occlusions, adverse weather, and complex urban environments.Autobrains' Air2Road Localization TechnologyFusing aerial images with ground images for highly precise and reliable localization.As the automotive industry accelerates toward fully autonomous vehicles, reliable and accurate localization is crucial for determining both vehicle position and the driving environment. Traditional localization systems, heavily reliant on Global Navigation Satellite Systems (GNSS) or crowd-sourced maps, face significant challenges such as limited coverage, high costs, and susceptibility to interference. Additionally, these systems rely on a single source of sensor-based information, leading to frequent errors and over-reliance on one type of input during driving."Air2Road is a game-changer for autonomous driving technology," said Igal Raichelgauz, CEO and Founder of Autobrains. "By providing multimodal redundancy and unmatched precision, Air2Road pushes the boundaries of what's achievable in vehicle navigation and safety, ensuring autonomous systems operate reliably under even in the most challenging conditions."Air2Road sets a new standard for vehicle localization by combining Signatures derived from two independent modalities - aerial imagery and ground-based perception - ensuring multimodal redundancy and accuracy. These Signatures are sparse binary hyperdimensional representations of both the driving environment and objects within it. This innovative approach overcomes many of the limitations inherent in traditional systems. These include:Multimodal Redundancy: By creating a joint representation of Signatures from two independent modalities (aerial images and ground-based data), Air2Road enables an unprecedented advantage of multimodal redundancy. Other existing systems use a fleet of vehicles with similar ground-based data sources, which increases repetitive mistakes and dependency on a single source of information.Full coverage: Unlike GNSS-based systems, Air2Road, with its Signature-based technology, continues to function effectively even under trees, bridges, between buildings, and in any other scenario with bad reception of the GNSS signal.Aerial Perception: Aerial images generate additional data layers-such as road markings, traffic signs, and obstacles-enabling safer and more efficient driving decisions and a redundancy to real-time perception.Scalable and Efficient: Traditional localization systems, such as crowd-sourced maps, require a fleet of vehicles to repeatedly traverse roads for data harvesting and building the map before the localization service becomes available for any vehicle. In contrast, Air2Road, enables the first vehicle on the road to achieve precise localization instantly, ensuring scalable deployment across various regions without compromising accuracy.Cost-Effective: Air2Road is compatible with affordable aerial imagery from multiple vendors, and its compressed Signatures technology enables large areas to be stored directly on the vehicle. This allows for a low-memory, low-bandwidth system, eliminating the need for constant cloud connectivity.Environment-Aware Path Planning: By leveraging real-time data on road conditions, traffic flow, and parking areas, Air2Road supports safer, more optimized navigation.Inspired by the human brain's ability to process multisensory information, Air2Road replicates mechanisms such as situational awareness and attention focus to ensure accurate decision-making. By filtering out irrelevant data and focusing on critical elements like road edges and buildings, the system significantly improves localization precision.With its data-driven approach and revolutionary dual-modality technology, Air2Road is poised to redefine the future of localization, facilitating safer and more reliable autonomous driving solutions.For more information about Autobrains and its cutting-edge Liquid AI and ADAS solutions, please visit autobrains.ai.Contact InformationSophia EichlerDirector of Marketingmedia@autobrains.ai+49 15167066494SOURCE: Autobrains Copyright 2024 ACN Newswire via SeaPRwire.com.
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Q2 Metals Drills 188.6 M Interval of Continuous Spodumene-Pegmatite and Concludes the 2024 Summer Drill Campaign at its Cisco Lithium Property, James Bay Quebec Canada ACN Newswire

Q2 Metals Drills 188.6 M Interval of Continuous Spodumene-Pegmatite and Concludes the 2024 Summer Drill Campaign at its Cisco Lithium Property, James Bay Quebec Canada

Highlights:An additional two (2) drill holes for approximately 1,188.1 metres (m) were completed during the Summer 2024 Drill Campaign and reported herein.Drill hole CS24-022 encountered 14 spodumene-pegmatite intervals, with the widest continuous interval of 52.3 m.Drill hole CS24-023 encountered 15 spodumene-pegmatite intervals, with the widest continuous interval of 188.6 m.Vancouver, BC, Sept 24, 2024 - (ACN Newswire via SeaPRwire.com) - Q2 Metals Corp. (TSXV:QTWO)(OTCQB:QUEXF)(FSE:458) ("Q2" or the "Company") is pleased to provide an update on the Summer 2024 Drill Program at the Cisco Lithium Property (the "Property" or the "Cisco Property") located within the greater Nemaska traditional territory of the Eeyou Istchee James Bay region of Quebec, Canada.The Summer 2024 Drill Campaign at the Cisco Lithium Property has concluded with a total of five (5) drill holes for approximately 2,609.9 m completed. Since May 2024, the Company has drilled a total of 6,359.7 m over 17 holes. All drill holes intercepted pegmatite with visual indications of spodumene mineralization identified."To say it's been a very productive first drill season for Q2 Metals at our Cisco Lithium Property is an understatement," said Q2 Metals President and CEO Alicia Milne. "The property continues to deliver, and we are pleased with what we're seeing and are eagerly awaiting the results from the now 13 drills holes that are yet to be reported.""We have been incredibly fortunate to be able to have built as much value in an early-stage project in four months. We have just started on the Cisco Project and look forward to receiving the assays on the holes drilled as we continue to move forward with Cisco," said Q2 Metals VP of Exploration Neil McCallum.The Summer 2024 Drill Campaign was focused on exploring the connection of the wide, continuous pegmatite zones that were encountered in holes CS24-010, CS24-018 and CS24-021. The last two holes of the season continued to confirm and expand the understanding of the main pegmatite zone.The geological team has completed the core cutting and logging of the last two (2) drill holes (CS24-022 to 023) of the Summer 2024 Campaign and the samples have been dispatched to the SGS Canada preparation laboratory located in Val-d'Or, QC for mineral analysis to confirm the presence of lithium. The visual results of drill holes CS24-022 and CS24-023 are herein reported.Summer 2024 Drilling UpdateFigure 1. Map of Drilling area, Cisco PropertyDrill hole CS24-022 was drilled on the same line as hole CS24-018 and collared 200 metres behind it, encountering 14 individual spodumene pegmatite intervals. Nine (9) intervals were greater than 10 m wide, with the widest individual interval measuring 52.3 m.CS24-023 was drilled at the same collar location as hole CS24-020 in order to test the southern strike direction of the main large continuous pegmatite zone. Drill hole CS24-023 encountered 15 individual spodumene pegmatite intervals of which eight (8) intervals were greater than 10 m wide, with the widest individual interval measuring 188.6 m.Table 1. Summary of Spodumene-Pegmatite intervals, Cisco PropertyFigure 2. Visual photo mapping the distance between hole CS24-023 and the CO1 outcrop measuring; 850 mTable 2. Summary of Drill Hole Collar Information, Cisco Property (CS24-022 to 023)The mineralized intervals in all the holes are not necessarily representative of the true width and the modelled pegmatite zones are being refined with every additional hole.Cautionary Statement: The presence of pegmatites does not confirm the presence of lithium (spodumene or other lithium minerals). Pegmatites are fractionated coarse grained igneous rocks commonly associated with lithium mineralization; however, many pegmatites do not contain mineralization. The presence of any mineralization can only be confirmed with assaying.About the Cisco PropertyThe Cisco Property is comprised of 222 mineral claims and is 11,374 hectares in size. It is located less than 10 km east of the Billy Diamond Highway, and is approximately 150 km north of Matagami, a small town that contains the closest rail link to much of James Bay. The Property lies within the greater Nemaska Community lands of the Eeyou Istchee Territory, James Bay, Quebec.The Property is situated along the Frotet Evans Greenstone Belt, comprised of a volcanic package dominated by mafic to felsic metavolcanic rocks, of the southern James Bay Lithium District, the same belt that hosts the Sirmac and Moblan lithium deposits, located 130 km and 180 km away, respectively.Sampling, Analytical Methods and QA/QC ProtocolsAll drill core samples are shipped to SGS Canada's preparation facility in Val D'Or, Quebec, for standard sample preparation (code PRP92) which includes drying at 105°C, crushing to 90% passing 2 mm, riffle split 500 g, and pulverize 85% passing 75 microns. The pulps are then shipped by air to SGS Canada's laboratory in Burnaby, BC, where the samples are homogenized and subsequently analyzed for multi-element (including Li and Ta) using sodium peroxide fusion with ICP-AES/MS finish (code GE_ICM91A50). The reported Li grade will be multiplied by the standard conversion factor of 2.153 which results in an equivalent Li2O grade. Drill core was saw-cut with half-core sent for geochemical analysis and half-core remaining in the box for reference. The same side of the core was sampled to maintain representativeness.A Quality Assurance / Quality Control (QA/QC) protocol following industry best practices was incorporated into the sampling program. Measures include the systematic insertion of quartz blanks and certified reference materials (CRMs) into sample batches at a rate of approximately 5% each. Additionally, analysis of pulp-split and reject-split duplicates was completed to assess analytical precision. The QP has verified the QA/QC results of the analytical work.Qualified PersonNeil McCallum, B.Sc., P.Geol, is a registered permit holder with the Ordre des Géologues du Québec and Qualified Person as defined by NI 43-101 and has reviewed and approved the technical information in this news release. Mr. McCallum is a director and VP Exploration for Q2.About Q2 Metals CorpQ2 Metals is a Canadian mineral exploration company focused on unlocking its portfolio of lithium projects in the Eeyou Istchee James Bay region of Quebec, Canada, that includes both its 100-per-cent-owned Mia Lithium Property and the Cisco Lithium Property.The Cisco lithium property is located approximately 150 km north of Matagami, Que., and comprises 222 mineral claims and is 11,374 ha in size. The property has district-scale potential with an already identified mineralized zone and a discovery drill result that included 120.3 metres at 1.72% lithium oxide (hole CS-23-010).FOR FURTHER INFORMATION, PLEASE CONTACT:Alicia MilnePresident & CEOAlicia@Q2metals.comTelephone: 1 (800) 482-7560E-mail: info@Q2metals.comJason McBrideCorporate CommunicationsJason@Q2metals.comWWW.Q2Metals.comFollow the Company: Twitter, LinkedIn, Facebook, and InstagramForward-Looking StatementsThis news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian legislation. Forward-looking statements are typically identified by words such as: "believes", "expects", "anticipates", "intends", "estimates", "plans", "may", "should", "would", "will", "potential", "scheduled" or variations of such words and phrases and similar expressions, which, by their nature, refer to future events or results that may, could, would, might or will occur or be taken or achieved. Accordingly, all statements in this news release that are not purely historical are forward-looking statements and include statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, any statements or plans regard the geological prospects of the Company's properties and the future exploration endeavors of the Company. Although the Company believes the expectations expressed in such forward-looking statements are based on reasonable assumptions, such statements are not guarantees of future performance and actual results or developments may differ materially from those in the forward-looking statements. Forward-looking statements are based on a number of material factors and assumptions.Forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause actual results to differ materially from those anticipated in such forward-looking statements. The forward-looking statements in this news release speak only as of the date of this news release or as of the date specified in such statement. Forward looking statements in this news release include, but are not limited to, drilling results on the Cisco Property and inferences made therefrom, the potential scale of the Cisco Property, the focus of the Company's current and future exploration and drill programs, the scale, scope and location of future exploration and drilling activities, the Company's expectations in connection with the projects and exploration programs being met, the Company's objectives, goals or future plans, statements, exploration results, potential mineralization, the estimation of mineral resources, exploration and mine development plans, timing of the commencement of operations and estimates of market conditions. Factors that could cause actual results to differ materially from those in forward-looking statements include failure to obtain necessary approvals, variations in ore grade or recovery rates, changes in project parameters as plans continue to be refined, unsuccessful exploration results, changes in project parameters as plans continue to be refined, results of future resource estimates, future metal prices, availability of capital and financing on acceptable terms, general economic, market or business conditions, risks associated with regulatory changes, defects in title, availability of personnel, materials and equipment on a timely basis, accidents or equipment breakdowns, uninsured risks, delays in receiving government approvals, unanticipated environmental impacts on operations and costs to remedy same. Readers are cautioned that mineral exploration and development of mines is an inherently risky business and accordingly, the actual events may differ materially from those projected in the forward-looking statements. Additional risk factors are discussed in the section entitled "Risk Factors" in the Company's Management Discussion and Analysis for its recently completed fiscal period, which is available under Company's SEDAR profile at www.sedarplus.ca.Should one or more of these risks or uncertainties materialize, or should assumptions underlying the forward-looking statements prove incorrect, actual results may vary materially from those described herein as intended, planned, anticipated, believed, estimated or expected. Although the Company has attempted to identify important risks, uncertainties and factors which could cause actual results to differ materially, there may be others that cause results not to be as anticipated, estimated or intended. The Company does not intend, and does not assume any obligation, to update this forward-looking information except as otherwise required by applicable law.Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.SOURCE: Q2 Metals Corp. Copyright 2024 ACN Newswire via SeaPRwire.com.
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Ching Lee Holdings (3728. HK) holds quality-driven strategies to acquire market share ACN Newswire

Ching Lee Holdings (3728. HK) holds quality-driven strategies to acquire market share

Quality Assurance and Professional StandardsHONG KONG, Sept 20, 2024 - (ACN Newswire via SeaPRwire.com) - Established in 1998, Ching Lee Engineering Limited ("Ching Lee Engineering"), asubsidiary of Ching Lee Holdings Limited ("Ching Lee")[1], possesses deepprofessional knowledge and extensive experience in construction engineering. Upholding "engineering quality" and "customer satisfaction" as core values, ChingLee Engineering continually enhances its standards to meet client demands. It alsosets "excellence in engineering" goals to ensure projects adhere to design, construction technical standards, and statutory regulations. Ching Lee is listed on theMain Board of the Hong Kong Stock Exchange (stock code: 3728.hk) and offersservices ranging from substructure building works services, superstructure buildingworks services, repair, maintenance, alteration and addition (RMAA) works servicesto various mechanical and electrical engineering projects.Client-first Approach with a Professional TeamRooted in Hong Kong for many years, Ching Lee is comprised of experiencedmanagers and core team members well-versed in construction knowledge and projectmanagement. The company is committed to providing the highest quality services andcontinuously expands its engineering capabilities to achieve sustainable businessgrowth. Embracing the philosophy of "professional service, client-first," Ching Leepursues key strategies for maximising growth potential and shareholder returns. Thesestrategies include bidding for larger projects, expanding the workforce, acquiringmachinery and suppliers to stabilise the supply chain, and enhancing market share tomaintain an active presence.Recognised Professional QualificationsChing Lee holds seven major professional qualifications, including being a"Registered General Building Contractor (RGBC)", a "Registered SpecialistContractor in the Foundation Works Category (RSC(F))" and a "Registered SpecialistContractor in the Site Formation Works Category (RSC(SF))", accredited by theHong Kong Buildings Department. These qualifications have enabled Ching Lee toundertake large-scale private construction projects over the years. Moreover, thecompany's commitment to quality is evident from its ISO 9001:2015 certification, andit also holds the ISO 14001:2015 certification, meeting the internationally recognisedstandards of leading Environmental Management Systems (EMS).Recently, Ching Lee has been added to the "Lists of Public Works Contractors (GroupB)"[2], which is approved for carrying out public works in the buildings category. Additionally, it has been added to the "List of Approved Specialist Contractors forPublic Works (Repair and Restoration of Historic Buildings)" by the BuildingsDepartment. These recognitions further demonstrate Ching Lee's excellence inachieving professional qualifications and industry recognition, highlighting thegroup's comprehensive strength in the construction engineering sector. Looking ahead, Ching Lee is poised to continue upholding its core values ofqualifications, expertise and quality, and it is committed to achieving even greateroutcomes in public and private projects. With a steadfast commitment to continuousimprovement, Ching Lee aims to tackle future challenges head-on and make asignificant contribution to the construction industry in Hong Kong.About Ching Lee Holdings Limited “Ching Lee” or “The Group”Ching Lee Holdings Limited, a limited liability company incorporated under the lawsof the Cayman Islands, is a contractor in Hong Kong with over 25 years of experiencein public and private sectors. The principal activities of Ching Lee Holdings and itssubsidiaries are the provision of construction and consultancy works and projectmanagement services in Hong Kong, engaged in providing substructure buildingworks services, superstructure building works services, and repair, maintenance, alteration and addition (RMAA) works services. Ching Lee Holdings Limited wastransferred from GEM board to the main board in HKEx on September 18, 2017 withstock code 3728.hk. Company website: http://www.chingleeholdings.comLists of Public Works Contractors (Group B)Ching Lee Engineering Limited is a contractor in Group B (Probationary Status) of the Lists of PublicWorks Contractors.- Group B for contracts of value up to HKD $400 million.Media enquiries:New Smile Limited Strategic IR & PR Consultancy Tel: +852 2126 7076Jenny Lai - jenny.lai@newsmilehk.comRichard Wong - richard.wong@newsmilehk.comElina Zhang - elina.zhang@newsmilehk.com Copyright 2024 ACN Newswire via SeaPRwire.com.
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Freedom Business Summit 2024: A Global Gathering For Entrepreneurs, Freedom Seekers, and Global Citizens ACN Newswire

Freedom Business Summit 2024: A Global Gathering For Entrepreneurs, Freedom Seekers, and Global Citizens

Estonia, Sept 24, 2024 - (ACN Newswire via SeaPRwire.com) - The Freedom Business Summit 2024 returns for another powerful edition, bringing together global citizens, entrepreneurs, and freedom seekers to explore strategies for global mobility, offshore structures, and the creation of location-independent lifestyles.Organized in official partnership with e-Residency Estonia, Incorp Indonesia, and EC Holdings Singapore, this two-day virtual summit will offer cutting-edge insights from the world’s leading experts on these emerging topics.This year’s summit aims to address key questions for those seeking personal and financial sovereignty. Over 4,000 attendees from 80 countries and 100 industries are expected to participate in live keynotes, expert-led panel discussions, and focused workshops.Topics range from relocation strategies and second citizenship to investment migration, Bali real estate opportunities, and the benefits of Estonia e-Residency for global entrepreneurs.Some of the featured speakers include:Sergei Zunajev from e-Residency Estonia, offering insights on the future of digital entrepreneurship.Max Chernov, revealing secrets to growing and building a successful YouTube channel.Show Nemoto, a mindset coach, guiding attendees on how to reprogram their minds to achieve business success.Pandu Bisramadani from Incorp Indonesia, presenting opportunities for investment and market entry strategies in Southeast Asia.Philippe A. May, founder of EC Holdings, discussing the strategic value of offshore investments.Joseph Shine, Ambassador of Palau Digital Residency, highlighting the benefits and process of obtaining Palau Residency ID.The event will focus on two main themes:- Day 1: Global Mobility, Investments, and Building Virtual Companies- Day 2: Offshore Strategies and Personal SovereigntyDenis Dovgal, the founder of Freedom Business Summit, emphasizes the importance of self-reliance in an increasingly unpredictable world:“Global mobility and personal sovereignty are no longer just dreams – they’re necessities for anyone who wants to thrive in today’s uncertain world. The strategies shared at Freedom Business Summit will empower you to navigate life on your terms.”Attendees will have access to exclusive knowledge on securing residency in emerging LATAM destinations such as Paraguay, leveraging the Flags Theory to maximize sovereignty, and creating global mobility strategies without reliance on expensive legal firms.Freedom Business Summit 2024 is the ultimate event for those committed to designing a life of freedom, on their own terms.About Freedom Business SummitThe Freedom Business Summit is an annual event that connects global citizens, entrepreneurs, and freedom seekers from across the world.The summit focuses on strategies for personal sovereignty, global mobility, offshore investments, and building location-independent businesses.The event brings together leading voices to educate, inspire, and provide actionable insights for those aiming to reclaim their freedom. For more information, visit www.freedomsummit.net.Media Contact:For all media inquiries, interviews, or sponsorship information, please contact: media@fsummit.net Copyright 2024 ACN Newswire via SeaPRwire.com.
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ISDNP Enters Strategic Partnership with Vietnam’s Red River Group through MOU SeaPRwire

ISDNP Enters Strategic Partnership with Vietnam’s Red River Group through MOU

Seoul, Korea – September 24, 2024 – (SeaPRwire) – ISDNP (https://isdnp.co.kr/), in partnership with JournalInNews, has taken a significant step towards entering the Vietnamese market by forging an alliance with a prominent local enterprise. On the 19th, the two companies jointly announced, the signing of a Memorandum of Understanding (MOU) on the 17th with Vietnam’s Red River Group to formalize their strategic collaboration. This agreement follows a high-level meeting on the 16th at Red River’s headquarters in Hanoi, Vietnam, between Insoo Park, the Chairman of JournalInNews, and LE CONG HOANG, Chairman of the Red River Group, during which both parties discussed the framework for a strategic partnership. The MOU outlines key areas of cooperation, including the introduction of ISDNP’s pedestrian signal voice guidance system in Vietnam and the promotion of JournalInNews’s JsetCoin within the Vietnamese business landscape. Both companies are poised to jointly deploy ISDNP’s pedestrian signal system nationwide, leveraging Red River Group’s extensive network and resources. Red River Group is a prominent, diversified conglomerate in Vietnam, with business interests spanning petroleum distribution, tourist vehicle rentals, smart parking solutions, automotive management centers, and emergency response infrastructure. Notably, its traffic rescue centers, which provide critical emergency assistance, are recognized as essential contributors to Vietnam’s transport and safety sectors. Through this partnership, both parties anticipate enhancing bilateral economic, social, and cultural exchanges while delivering substantive outcomes. ISDNP has committed to supplying the requisite technical expertise and information necessary for the successful deployment of the pedestrian signal voice guidance system, while Red River Group has pledged comprehensive support to ensure the project’s smooth execution. Additionally, JournalInNews has designated Red River Group as its strategic partner to facilitate the expansion of JsetCoin within the Vietnamese market. Both parties are exploring various collaborative avenues, including the potential establishment of a local subsidiary, aimed at fostering a synergistic partnership and ensuring the efficient exchange of essential information. This MOU is expected to strengthen economic ties between the two countries and serve as a catalyst for sustained growth. Both parties have committed to maintaining close cooperation to ensure the successful realization of the agreement’s objectives. Media contact Brand: ISDNP Contact: Media team Email: support@isdnp.co.kr Website: https://isdnp.co.kr/ SOURCE: ISDNP The article is provided by a third-party content provider. SeaPRwire ( https://www.seaprwire.com/ ) makes no warranties or representations in connection therewith. Sectors: Top Story, Corporate News SeaPRwire provides real time press release distribution for companies and organizations to 6,500+ media outlets & 3.5 million professional desktops in 90 regions. It distributes press releases in different languages, including: IndonesiaFolk, IndoNewswire, SEATribune, IDNewsZone, LiveBerita, DailyBerita, TaiwanPR, SinchewBusiness, AsiaEase, BuzzHongKong, SingapuraNow, TIHongKong, TaipeiCool, TWZip, AsiaFeatured, dePresseNow, THNewson, KULPR, VNFeatured, MENAEntry, HunaTimes, DubaiLite, ArabicDir, BeritaDaring, TekanAsia, JamKopi ...
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The Clean Cities And Urban Development Forum 2024 – Driving Innovation For Sustainable Waste Management & Urban Development ACN Newswire

The Clean Cities And Urban Development Forum 2024 – Driving Innovation For Sustainable Waste Management & Urban Development

KUALA LUMPUR, Sept 24, 2024 - (ACN Newswire via SeaPRwire.com) - The Clean Cities and Urban Development Forum 2024 is set to take place on November 20 - 21, 2024, at the prestigious M Resort Hotel, Kuala Lumpur. This exclusive event promises to bring together global leaders, industry experts, policymakers, and innovators, all united by a shared vision of creating cleaner, greener, and more sustainable cities.More than just a conference, the Clean Cities and Urban Development Forum 2024 is a call to action. In an era marked by rapid urbanization and environmental challenges, it’s essential for cities and communities to adopt smarter and more sustainable approaches to waste management and urban development. As the world’s urban population grows, cities are facing increasing pressure to address waste generation, resource consumption, and environmental degradation. From air pollution to overflowing landfills, the challenges are clear. However, this forum will provide a unique opportunity to explore the solutions that can transform urban areas into sustainable, eco-friendly environments for future generations.Event Highlights:The Clean Cities and Urban Development Forum 2024 will focus on innovative strategies that aim to reduce waste, promote recycling, and minimize environmental impacts. This year’s theme revolves around the integration of smart technologies and zero-waste initiatives to foster urban growth through safe and effective practices.Key topics to be covered include:- Smart Technologies for Waste Management: Industry leaders will present groundbreaking solutions to optimize waste management through smart technologies such as IoT (Internet of Things), AI-powered waste segregation systems, and real-time data analytics for efficient collection and disposal. These solutions promise to revolutionize how cities manage waste while reducing costs and improving environmental outcomes.- Advanced Strategies for Waste Segregation and Recycling: Attendees will explore cutting-edge techniques for effective waste segregation and recycling that aim to significantly reduce the amount of waste sent to landfills. Best practices from cities leading the charge in sustainable waste practices will be highlighted, providing actionable insights for attendees to implement in their own municipalities.- Waste-to-Energy Innovations: One of the most exciting discussions will focus on the pioneering innovations in waste-to-energy and biogas production. Experts will demonstrate how organic waste can be converted into valuable resources such as electricity, biofuels, and compost. These technologies offer a promising pathway for cities to turn their waste problems into sustainable energy solutions.- CO2 Reduction and the Valorisation of Solid Waste: The forum will delve into advanced CO2 reduction strategies, including the valorisation of solid waste into biofuels, compost, and recyclable materials. These techniques not only mitigate greenhouse gas emissions but also create economic opportunities through the circular economy, driving sustainability forward.- Collaborative Urban Development: Attendees will also have the chance to hear from policymakers and urban planners about successful urban development strategies that prioritize sustainable growth. By integrating green spaces, energy-efficient infrastructure, and sustainable building practices, cities can reduce their carbon footprint while enhancing the quality of life for residents.Why AttendThe Clean Cities and Urban Development Forum 2024 is a must-attend event for anyone involved in the fields of urban development, environmental sustainability, waste management, and renewable energy. It is designed for those who want to stay at the forefront of sustainability innovations and urban growth strategies that align with the United Nations’ Sustainable Development Goals (SDGs).By attending, participants will not only witness groundbreaking discussions but also become part of the change driving sustainable urban growth across Asia and beyond. This is an unparalleled opportunity for stakeholders in the public and private sectors, as well as those involved in urban planning, environmental management, and technology development, to come together and shape the future of urban sustainability.Here’s what makes this forum unique:1. Access to Industry Experts: The forum will feature speakers from multi-diversified industries across Asia and beyond, providing participants with direct access to some of the brightest minds in sustainability and urban planning.2. Networking Opportunities: With a diverse group of attendees including industry leaders, policymakers, and sustainability experts, participants will have numerous opportunities to connect, collaborate, and share ideas with peers from around the world.3. Actionable Insights: Each session is designed to provide tangible takeaways that attendees can implement in their own projects or businesses. From learning how to integrate smart waste management solutions to exploring the latest advancements in waste-to-energy, this forum offers tools and strategies for real-world application.4. Future-Focused Discussions: The forum will not only address today’s challenges but will also explore emerging trends and technologies that will shape the future of sustainable urban development. From biogas production to next-generation recycling technologies, attendees will leave with a clear understanding of where the industry is headed.Keynote SpeakersThe event will showcase an esteemed lineup of speakers who are pioneers in their respective fields, offering valuable insights and strategies for sustainable development. Speakers include:- Anwar Syahrin Abdul Ajib, Managing Director & Group Chief Executive Officer at Malakoff. With extensive experience in leading sustainable energy initiatives, Anwar will discuss the role of energy in urban development and how clean energy can drive sustainable cities.- Dr. Maria Neira, Director of the Department of Environment, Climate Change, and Health at the World Health Organization. Dr. Neira will focus on the intersection of public health and sustainable waste management, emphasizing the need for cities to adopt eco-friendly waste practices to protect human health.- Tengku Erina Tengku Nasrudin, Chief Executive Officer at AECA SOLUTIONS. As a leader in environmental solutions, Tengku Erina will present on innovative strategies for waste-to-energy transformation and how cities can harness waste as a resource.- Vinod Sekhar, Chairman & Group CEO at Petra Group. Vinod will share his insights on the circular economy and how businesses can lead the way in creating sustainable, waste-free communities through innovative technologies.- Dr. Margaret Kuyor, Deputy Secretary (Circular Economy Policy) at the Urban Sustainability & Green Environment Division, Ministry of Housing & Local Government. Dr. Kuyor will discuss Malaysia’s ongoing initiatives in circular economy and urban sustainability, with a focus on policy frameworks that can foster greener cities.SessionsThe Clean Cities and Urban Development Forum 2024 will present a wide range of sessions focused on innovative waste management strategies. Topics include biological waste treatments, waste-to-energy technologies, AI-powered sludge and wastewater management, and reducing carbon and water footprints. The forum will also explore biofuel production, advanced recycling techniques, e-waste recovery, hydrogen production, and the role of municipalities in sustainability.ConclusionThe Clean Cities and Urban Development Forum 2024 is more than just an event—it’s a global platform for action. Join us to learn from the best minds in the industry, share your own experiences, and play a pivotal role in creating a cleaner, greener, and more sustainable future for urban environments across the world.About The Clean Cities and Urban Development Forum 2024The Clean Cities and Urban Development Forum 2024 is organized by CT Event Asia, a leading provider of high-level events in the field of environmental sustainability and urban development. With a focus on knowledge-sharing and fostering innovation, CT Event Asia brings together experts from diverse industries to address the most pressing challenges of our time.For more information, please contact:Amina KanteSenior Marketing ManagerCT Event AsiaPhone: +601161888699Email: amina@ctasia.com.myWebsite: https://www.cleancitiesforum.com/Registration: Early bird discounts are available until October 15th, 2024. Register at: https://www.cleancitiesforum.com/request Copyright 2024 ACN Newswire via SeaPRwire.com.
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Anson Receives US$330M Letter of Interest from Export-Import Bank of the United States ACN Newswire

Anson Receives US$330M Letter of Interest from Export-Import Bank of the United States

Highlights:A non-binding Letter of Interest received from the US EXIM Bank for up to US$330M in long term debt financing for the construction of a lithium production plant at the Paradox Basin in Utah, USA.US EXIM is the official export credit agency of the US Federal Government, whose objectives include strengthening America’s Supply Chains through it’s “Make More in America” Initiative.Anson continues to advance development of its globally significant lithium projects located in the Paradox Basin, Utah.NEWPORT BEACH, CA, Sept 24, 2024 - (ACN Newswire via SeaPRwire.com) - Anson Resources Limited (ASX:ASN) ("Anson Resources" or "the Company") is pleased to announce that its 100% owned US subsidiary, A1 Lithium, has received a non-binding and conditional Letter of Interest (LoI) from the Export-Import Bank of the United States (US EXIM) to provide a debt funding package of up to US$330 million (A$500 million1) for the construction of a lithium production plant in Utah, USA, under the "Make More in America" Initiative.The LoI from US EXIM represents a material step in Anson's project funding strategy and is recognition of the strong engagement the Company has had with the US Government and with industry partners in the United States.Anson's Executive Chairman and CEO Bruce Richardson commented:"We are delighted to receive this Letter of Interest from US EXIM following extensive collaboration with multiple government and industry stakeholders in the United States. This LoI reflects our continued strong development, permitting progress and community engagement efforts in the United States and Southern Utah in particular.The United States seeks to develop a domestic and reliable source of critical minerals and the Paradox Basin, which we believe is the largest source of lithium in the United States, has a significant role to play. Our DLE technology will produce one of the most environmentally friendly sources of lithium globally. This will support the development of the new energy economy, from electric vehicles to drones and defense."Anson's Chief Financial Officer Matthew Beattie commented:"This LoI reflects the Paradox Project in Sothern Utah's potential to be a major source of new, high paying jobs and stimulate investment in the region. While non-binding, the Company views the LoI as an important step in advancing our project financing plan for the development of our world class Paradox Basin projects. If finalised, the US EXIM facility will make up a substantial portion of the overall funding requirements."The LoI from EXIM does not represent a financing commitment and is a preliminary step in the formal EXIM application process. The debt financing is subject to the satisfactory completion of due diligence, the negotiation and settlement of final terms, and the negotiation of definitive documentation. There can be no assurance that the debt financing will be completed on the terms as described above or at all. The Company will update the market upon reaching a definitive agreement with US EXIM for funding support.About the Export-Import Bank of the United StatesUS EXIM is the official export credit agency of the United States of America. EXIM is an independent Executive Branch agency with a mission of supporting American jobs by facilitating the export of U.S. goods and services.As published in its 2023 Annual Report, EXIM has current exposure to US$1,476.7 billion in lending across 148 countries around the world. The default rate across the portfolio is 0.98%, reflecting the high standards of credit required to obtain EXIM financing. Furthermore, EXIM's charter requires that it supplement and encourage, not displace, private capital.For further information please contact:Will MazeHead of Investor RelationsE: investors@ansonresources.comPh: +61 7 3132 7990www.ansonresources.comFollow us on Twitter @anson_irSOURCE: Anson Resources Copyright 2024 ACN Newswire via SeaPRwire.com.
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Experian Launches Global Ultimate Beneficial Ownership Compliance Solution for Enhanced KYC/KYB Verification ACN Newswire

Experian Launches Global Ultimate Beneficial Ownership Compliance Solution for Enhanced KYC/KYB Verification

SINGAPORE, Sept 24, 2024 - (ACN Newswire via SeaPRwire.com) - Experian Singapore (Experian) recently introduced Global UBO (Ultimate Beneficial Ownership), a comprehensive report to the market, designed to revolutionise due diligence and compliance processes in onboarding, portfolio management, and customer lifecycle management.This innovative resource provides detailed insights and evaluations of cross-border UBOs in over 200 markets, helping small and medium enterprises (SMEs), corporations and financial institutions navigate the complexities of regulatory compliance and risk management.In an increasingly globalised and regulated marketplace, the importance of thoroughly understanding the complexities of business structures cannot be overstated. Experian’s Global UBO reports offer a standardised, detailed analysis of UBOs in one comprehensive report. These reports equip organisations with the critical information needed to make well-informed decisions, ensuring they meet the highest standards of due diligence, compliance, Know Your Customer (KYC) and Know Your Business (KYB) needs.It’s no longer only financial institutions who have to comply with UBO regulations. Regulators are bringing their rules in line with global efforts to promote beneficial ownership transparency across other sectors – namely legal, real estate, corporate service providers and accountancy.In Singapore, real estate developers with more than four units have to comply with the anti-money laundering and terrorism financing provisions. (ref https://www.ura.gov.sg/Corporate/Guidelines/Developers/Anti-Money-Laundering)“Experian Global UBO helps businesses know exactly who they are doing business with, ensuring that their business partners comply with national and international laws on money laundering (AML), bribery and corruption, and regulations related to KYC/KYB. It automates and enhances the due diligence process by providing a reliable and comprehensive UBO report,” said Kabir Khanna, General Manager, Experian Credit Services Singapore.Key benefits of the Global UBO report includes:Enhanced Due Diligence: Comprehensive evaluations help identify potential risks and ensure thorough vetting of UBOs during the onboarding process.Streamlined Portfolio Management: Leads to more effective and efficient risk management and decision-making, fostering a more secure and stable portfolio.Improved Customer Lifecycle Management: Insights ensure that organisations remain compliant with evolving regulations and maintain high standards of customer relationship management.These reports are an essential tool for financial institutions, regulatory bodies, and businesses committed to maintaining compliance and managing risk in today's complex environment. By leveraging Experian’s Global UBO reports, organisations can confidently navigate the challenges of regulatory compliance, mitigate risks, and enhance their overall operational integrity.In conjunction with the launch of Global UBO reports in Southeast Asia, Experian is also introducing a global monitoring service for Credit Reports. These are refreshed investigative credit reports produced over a predetermined period to help monitor critical business relationships in a proactive manner.For more information about Experian’s Global UBO solution and the new Global Monitoring Service for Credit Reports, please visit www.experian.com.sg.For media enquiries: PRecious Communications for Experianexperian@preciouscomms.com About ExperianExperian is a global data and technology company, powering opportunities for people and businesses around the world. We help redefine lending practices, uncover and prevent fraud, simplify healthcare, deliver marketing solutions, and gain deeper insights into the automotive market, all using our unique combination of data, analytics, and software. We also assist millions of people to realise their financial goals and help them to save time and money. We operate across a range of markets, from financial services to healthcare, automotive, agribusiness, insurance, and many more industry segments. We invested in talented people and new advanced technologies to unlock the power of data and innovate. As a FTSE 100 Index company listed on the London Stock Exchange (EXPN), we have a team of 22,500 people across 32 countries. Our corporate headquarters are in Dublin, Ireland. Learn more at experianplc.com. Copyright 2024 ACN Newswire via SeaPRwire.com.
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Ensign InfoSecurity Recognised as Honouree in NextGen Tech 30, ASEAN’s First Public-Private Initiative to Recognise Growth Companies of the Region ACN Newswire

Ensign InfoSecurity Recognised as Honouree in NextGen Tech 30, ASEAN’s First Public-Private Initiative to Recognise Growth Companies of the Region

SINGAPORE, Sept 24, 2024 - (ACN Newswire via SeaPRwire.com) - Ensign InfoSecurity (“Ensign”), one of Asia’s largest comprehensive cybersecurity service providers, has been named an honouree in the prestigious NextGen Tech 30, the region’s first initiative spotlighting home-grown growth stage companies transforming the ASEAN economy. Organised by Granite Asia in partnership with key players such as 65 Equity Partners, DBS Bank, EDBI, Infocomm Media Development Authority, KKR, Northstar Group, Singapore Business Federation and Singapore Exchange, NextGen Tech 30 identifies companies driving exceptional innovation and growth across Automation, Enterprise Solutions, and Food Tech & Brands.Ensign’s recognition in the Enterprise Solutions category of the NextGen Tech 30 marks a significant milestone in its growth across ASEAN. This accolade reinforces the company’s leadership in cybersecurity innovation and its role in strengthening digital resilience across the region. Powered by its in-house research and development, Ensign delivers proprietary solutions designed to address the growing complexity of cyber threats. These technologies, underpinned by patented methodologies, provide cutting-edge protection for both public and private sector organisations.Since its inception in 2018, Ensign has evolved into a world-class cybersecurity company with an Asia-first approach. Acting as a single point of accountability, Ensign provides a comprehensive, threat-informed suite of services spanning advisory, assurance, architecture design, systems integration, managed security, and incident response. Leveraging AI, data science, and deep threat analysis, the company delivers tailored solutions to address the specific cybersecurity challenges faced by its clients.A key highlight of Ensign’s recent innovations is the launch of Aletheia, a cutting-edge deepfake detection solution designed to safeguard enterprises, governments and consumers from the growing threat of AI-manipulated media. Aletheia represents a significant advancement in cybersecurity, leveraging AI to detect deepfakes in real time, within seconds and achieving up to 90% accuracy."We are honoured to be named a NextGen Tech 30 honouree. This recognition underscores our dedication to pushing the boundaries of cybersecurity innovation while supporting the digital growth of the ASEAN economy. At Ensign, we are focused on developing AI-driven solutions that not only address today’s threats but also equip organisations to stay ahead of future challenges,” said Tammie Tham, Group Chief Executive Officer of Ensign InfoSecurity.The NextGen Tech 30 is backed by a panel of esteemed industry leaders and investors including Mukul Chawla, Head of Asia Pacific Growth Equity at KKR; Kok Ping Soon, CEO of Singapore Business Federation; Jenny Lee, Senior Managing Partner of Granite Asia; Lew Chuen Hong, Chief Executive of Infocomm Media Development Authority; Paul Ng, CEO of EDBI; Ng Yao Loong, CFO of SGX Group; Tan Su Shan, Group Head of Institutional Banking at DBS Bank; Adrienne Teh, Managing Director of 65 Equity Partners; Wong Chee-Yann, Group CIO at Northstar Group, further cementing the significance of this accolade.About Ensign InfoSecurityEnsign InfoSecurity is the largest comprehensive cybersecurity service provider in Asia. Headquartered in Singapore, Ensign offers bespoke solutions and services to address their clients’ cybersecurity needs. Their core competencies are in the provision of cybersecurity advisory and assurance services, architecture design and systems integration services, and managed security services for advanced threat detection, threat hunting, and incident response. Underpinning these competencies is in-house research and development in cybersecurity. Ensign has two decades of proven track record as a trusted and relevant service provider, serving clients from the public and private sectors in the Asia Pacific region.For more information, visit www.ensigninfosecurity.com or email media@ensigninfosecurity.com. Copyright 2024 ACN Newswire via SeaPRwire.com.
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PM UK Keir Starmer dalam air panas kerana menerima barangan percuma, menegaskan dia tidak melakukan kesalahan Berita

PM UK Keir Starmer dalam air panas kerana menerima barangan percuma, menegaskan dia tidak melakukan kesalahan

(SeaPRwire) - Walaupun baru memegang jawatan kurang dari tiga bulan, Keir Starmer telah menimbulkan tanda tanya dengan menerima sumbangan dalam bentuk pakaian dan hadiah lain dari seorang ahli perniagaan kaya. , yang memenangi kuasa dalam kemenangan besar atas janji untuk memulihkan kepercayaan dalam politik, telah menafikan sebarang kesalahan atas ribuan pound pakaian dan cermin mata yang dibayar oleh Waheed Alli, seorang usahawan media dan penderma lama kepada parti itu. Sakit kepala bagi Starmer bertambah buruk setelah mendedahkan ketua kakitangannya, Sue Gray, dibayar 170,000 pound, atau $225,000, setahun, yang lebih kurang 3,000 pound lebih daripada gaji perdana menteri. Seorang bekas pegawai kanan kerajaan, Gray paling dikenali kerana memimpin siasatan mengenai parti yang melanggar sekatan di bangunan kerajaan semasa .Penemuan Gray membantu menjatuhkan Perdana Menteri Konservatif Boris Johnson, dan pergerakannya kemudian untuk bekerja untuk Starmer menyebabkan Konservatif mendakwa siasatan "partygate" itu berat sebelah dari segi politik – sesuatu yang dinafikan oleh Gray.Parti Buruh, sementara itu, telah menuduh Konservatif mencetuskan kontroversi untuk mencemarkan kerajaan. Ahli parlimen boleh menerima hadiah tetapi mesti mengisytiharkan sumbangan dan pendapatan luar parlimen dalam tempoh 28 hari – tarikh akhir yang terlepas oleh Starmer. Beliau menyalahkan kelewatan itu atas kakitangannya yang mencari nasihat mengenai apa yang perlu diisytiharkan. "Saya sangat konsisten dengan mematuhi peraturan," kata Starmer minggu ini, menolak cadangan bahawa perdana menteri harus mendapat bajet almari pakaian. Starmer menolak dakwaan perbezaan pendapat di kalangan kakitangannya mengenai Gray dan gajinya, menegaskan bahawa beliau "sangat mengawal". "Saya fokus dan setiap hari mesej dari saya kepada pasukan adalah sama, iaitu kita perlu menyampaikan," katanya kepada BBC pada hari Khamis. "Kita telah dipilih berdasarkan mandat besar untuk menyampaikan perubahan, saya bertekad bahawa kita akan melakukan itu."Skala hadiah yang diterima oleh Starmer dan isterinya, Victoria, telah mengejutkan bahkan penyokongnya. Sky News melaporkan bahawa Starmer telah mengisytiharkan "hadiah, faedah dan hospitaliti" bernilai lebih daripada 100,000 pound sejak Disember 2019, lebih banyak daripada mana-mana ahli parlimen lain. Sumbangan itu termasuk beribu-ribu pound tiket untuk perlawanan Liga Perdana yang melibatkan pasukan bola sepak kesayangan perdana menteri, Arsenal. Selepas kontroversi meletus, Parti Buruh mengatakan Starmer tidak akan menerima lagi pakaian percuma. Timbalan Perdana Menteri Angela Rayner, yang juga menerima sumbangan untuk membayar pakaian, memberitahu BBC: "Saya faham bahawa orang ramai marah [tetapi] sumbangan untuk hadiah dan hospitaliti dan sumbangan wang telah menjadi ciri politik kita sejak sekian lama." "Orang ramai boleh mencarinya dan melihat apa yang diterima oleh orang ramai untuk sumbangan, dan ketelusan adalah sangat penting," kata Rayner. Pemimpin Buruh berharap persidangan tahunan selama empat hari, yang bermula pada hari Ahad, akan menyuntik semangat yang sangat diperlukan untuk parti itu. Digital telah menghubungi 10 Downing St. dan Alli untuk mendapatkan komen lanjut. Artikel ini disediakan oleh pembekal kandungan pihak ketiga. SeaPRwire (https://www.seaprwire.com/) tidak memberi sebarang waranti atau perwakilan berkaitan dengannya. Sektor: Top Story, Berita Harian SeaPRwire menyampaikan edaran siaran akhbar secara masa nyata untuk syarikat dan institusi, mencapai lebih daripada 6,500 kedai media, 86,000 penyunting dan wartawan, dan 3.5 juta desktop profesional di seluruh 90 negara. SeaPRwire menyokong pengedaran siaran akhbar dalam bahasa Inggeris, Korea, Jepun, Arab, Cina Ringkas, Cina Tradisional, Vietnam, Thai, Indonesia, Melayu, Jerman, Rusia, Perancis, Sepanyol, Portugis dan bahasa-bahasa lain.
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AS mengirim lebih banyak tentera ke Timur Tengah, Netanyahu memberi amaran kepada rakyat Lubnan ketika konflik Israel-Hezbollah meningkat Berita

AS mengirim lebih banyak tentera ke Timur Tengah, Netanyahu memberi amaran kepada rakyat Lubnan ketika konflik Israel-Hezbollah meningkat

(SeaPRwire) - Amerika Syarikat sedang menghantar lebih banyak tentera ke Timur Tengah, ketika Perdana Menteri Israel mengeluarkan amaran kepada rakyat Lubnan mengenai konflik yang semakin meningkat dengan Hizbullah. "Berikutan peningkatan ketegangan dan demi langkah berjaga-jaga, kami menghantar sejumlah kecil anggota tentera Amerika Syarikat tambahan ke hadapan untuk menambah kekuatan pasukan kami yang sudah berada di rantau ini. Tetapi atas sebab keselamatan operasi, saya tidak akan memberi komen atau memberikan spesifikasi," kata Mejar Jeneral Pat Ryder kepada pemberita semasa sidang akhbar tanpa kamera pada Isnin. Amerika Syarikat sudah mempunyai 40,000 tentera di rantau ini. Pengerahan baru ini berlaku selepas serangan besar-besaran oleh pasukan Israel ke atas sasaran di dalam Lubnan yang telah membunuh ratusan orang dan ketika Israel sedang bersiap sedia untuk melakukan operasi selanjutnya. Netanyahu mengeluarkan kenyataan video pada Isnin yang ditujukan kepada "rakyat Lubnan". "Perang Israel bukanlah dengan anda. Ia dengan Hizbullah. Sudah terlalu lama, Hizbullah menggunakan anda sebagai perisai manusia. Ia meletakkan roket di ruang tamu anda dan peluru berpandu di garaj anda," kata Netanyahu. "Roket dan peluru berpandu itu disasarkan terus ke bandar kami, terus ke rakyat kami. Untuk mempertahankan rakyat kami daripada serangan Hizbullah, kami mesti memusnahkan senjata itu.""Mulai pagi ini, IDF telah memberi amaran kepada anda untuk keluar dari bahaya," tambah Netanyahu. "Saya mendesak anda – ambil amaran ini dengan serius. Jangan biarkan Hizbullah membahayakan nyawa anda dan nyawa orang yang anda sayangi. Jangan biarkan Hizbullah . Sila, keluar dari bahaya sekarang. Setelah operasi kami selesai, anda boleh kembali dengan selamat ke rumah anda." Beliau bercakap ketika pesawat perang Israel terus menyerang sasaran Hizbullah di selatan dan timur Lubnan. mengesahkan bahawa kabinet Netanyahu meluluskan "keadaan khas" – serupa dengan keadaan darurat – di barisan hadapan Israel pada Isnin. Menurut kerajaan Israel, pengisytiharan tersebut memperluaskan kuasa Angkatan Pertahanan Israel (IDF) secara signifikan untuk memberikan arahan awam, membenarkan tentera untuk melarang perhimpunan, mengehadkan pembelajaran dan mengeluarkan "arahan tambahan yang diperlukan untuk menyelamatkan nyawa".Jabatan Negara Amerika Syarikat memberi amaran kepada rakyat Amerika untuk meninggalkan Lubnan kerana risiko perang serantau meningkat."Berikutan sifat konflik yang tidak dapat diramalkan antara Hizbullah dan Israel dan letupan terkini di seluruh Lubnan, termasuk Beirut, Kedutaan Besar Amerika Syarikat menggesa rakyat Amerika untuk meninggalkan Lubnan selagi pilihan komersial masih tersedia," Jabatan Negara memberi amaran pada hari Sabtu. Ryder tidak akan mengatakan sama ada pasukan tambahan mungkin menyokong evakuasi warga tersebut jika diperlukan.Tambahan pula pada Isnin, , dua kapal pemusnah dan kapal penjelajah berlayar dari Norfolk, Virginia, menuju ke Mediterranean dalam penempatan yang dijadualkan secara tetap, membuka kemungkinan bahawa Amerika Syarikat boleh mengekalkan kedua-dua Truman dan kapal pengangkut pesawat USS Abraham Lincoln, yang berada di Teluk Oman, berdekatan sekiranya berlaku keganasan selanjutnya, menurut The Associated Press. Setiausaha Pertahanan Lloyd Austin mengadakan panggilan berturut-turut dengan Menteri Pertahanan Israel Yoav Gallant pada hujung minggu ketika beliau menekan untuk gencatan senjata dan pengurangan ketegangan di rantau ini, kata Ryder."Memandangkan ketegangan, memandangkan peningkatan, seperti yang saya tekankan, terdapat potensi untuk konflik serantau yang lebih luas. Saya tidak fikir kita berada di sana lagi, tetapi ia adalah keadaan yang berbahaya," kata Ryder.Kehadiran Amerika Syarikat di Timur Tengah bertujuan untuk membantu mempertahankan Israel dan melindungi kakitangan dan aset Amerika Syarikat dan sekutunya. Kapal perang Tentera Laut tersebar di seluruh rantau ini, dari Laut Mediterranean timur hingga ke Teluk Oman, dan kedua-dua pesawat pejuang Tentera Udara dan Tentera Laut ditempatkan secara strategik di beberapa lokasi untuk lebih bersedia untuk bertindak balas terhadap sebarang serangan.' Yonat Friling dan Artikel ini disediakan oleh pembekal kandungan pihak ketiga. SeaPRwire (https://www.seaprwire.com/) tidak memberi sebarang waranti atau perwakilan berkaitan dengannya. Sektor: Top Story, Berita Harian SeaPRwire menyampaikan edaran siaran akhbar secara masa nyata untuk syarikat dan institusi, mencapai lebih daripada 6,500 kedai media, 86,000 penyunting dan wartawan, dan 3.5 juta desktop profesional di seluruh 90 negara. SeaPRwire menyokong pengedaran siaran akhbar dalam bahasa Inggeris, Korea, Jepun, Arab, Cina Ringkas, Cina Tradisional, Vietnam, Thai, Indonesia, Melayu, Jerman, Rusia, Perancis, Sepanyol, Portugis dan bahasa-bahasa lain.
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Pemimpin Marxis disumpah sebagai presiden negara dengan 22 juta penduduk Berita

Pemimpin Marxis disumpah sebagai presiden negara dengan 22 juta penduduk

(SeaPRwire) - Politician Marxist, Anura Kumara Dissanayake secara rasminya memegang jawatan sebagai presiden Sri Lanka pada hari Isnin.Dissanayake, 55, yang parti politiknya dituduh membawa negara itu ke dalam krisis ekonomi. Pemimpin baharu ini adalah dari Parti Barisan Pembebasan Rakyat, sebuah kumpulan Marxist yang melancarkan dua pemberontakan bersenjata pada tahun 1970-an dan 1980-an."Kami telah memahami sepenuhnya bahawa kami akan menerima negara yang mencabar," kata Dissanayake semasa upacara angkat sumpahnya. "Kami tidak percaya bahawa kerajaan, satu parti atau individu akan dapat menyelesaikan krisis yang mendalam ini. mengucapkan tahniah kepada Dissanayake atas kemenangannya, dengan mengatakan pada hari Isnin bahawa China berharap dapat bekerja sama "untuk meneruskan persahabatan tradisional kita bersama-sama." Amerika Syarikat dan India sebelum ini telah mengucapkan tahniah kepada Dissanayake.Terletak di selatan India, ramai pengundi di negara berpenduduk 22 juta orang - lebih kurang sama dengan saiz West Virginia - mengatakan mereka merasakan rasa tidak puas hati dengan budaya politik negara itu ketika negara itu perlahan-lahan keluar dari krisis ekonominya.Reuters melaporkan bahawa inflasi meningkat setinggi 70% selepas kejatuhan 2022 disebabkan kekurangan dolar yang teruk. Walau bagaimanapun, inflasi telah menurun sejak itu, dan KDNK negara dijangka berkembang "buat pertama kalinya dalam tiga tahun."Pelantikan Dissanayake adalah peralihan kuasa standard pertama di Sri Lanka sejak 2022, apabila perusuh memaksa bekas Presiden Gotabaya Rajapaksa untuk meletak jawatan dan melarikan diri dari negara itu. Wickremesinghe kemudian menggantikannya dalam kesudahannya.Cabaran utama pertama Dissanayake adalah untuk melaksanakan janji kempennya untuk mengurangkan langkah-langkah penjimatan yang dikenakan oleh pendahulunya Wickremesinghe di bawah perjanjian bantuan dengan Tabung Kewangan Antarabangsa, yang merupakan pemiutang terbesar negara itu.The Associated Press dan Reuters menyumbang kepada laporan iniArtikel ini disediakan oleh pembekal kandungan pihak ketiga. SeaPRwire (https://www.seaprwire.com/) tidak memberi sebarang waranti atau perwakilan berkaitan dengannya. Sektor: Top Story, Berita Harian SeaPRwire menyampaikan edaran siaran akhbar secara masa nyata untuk syarikat dan institusi, mencapai lebih daripada 6,500 kedai media, 86,000 penyunting dan wartawan, dan 3.5 juta desktop profesional di seluruh 90 negara. SeaPRwire menyokong pengedaran siaran akhbar dalam bahasa Inggeris, Korea, Jepun, Arab, Cina Ringkas, Cina Tradisional, Vietnam, Thai, Indonesia, Melayu, Jerman, Rusia, Perancis, Sepanyol, Portugis dan bahasa-bahasa lain.
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