MHI Receives Order to Supply MOX Fuel Assemblies for Unit 3 of Genkai Nuclear Power Station, Kyushu Electric Power Co. Inc. JCN Newswire

MHI Receives Order to Supply MOX Fuel Assemblies for Unit 3 of Genkai Nuclear Power Station, Kyushu Electric Power Co. Inc.

TOKYO, Oct 18, 2024 - (JCN Newswire via SeaPRwire.com) - Mitsubishi Heavy Industries, Ltd. (MHI) has received an order from Kyushu Electric Power Co. Inc. (Kyushu) to supply MOX(1) fuel assemblies for Unit 3 of the Genkai Nuclear Power Station. Under this contract, MHI will perform design of MOX fuel, and have components such as cladding tubes manufactured by Mitsubishi Nuclear Fuel Co., Ltd. (MHI Group) provided to Orano, who plans to fabricate 40 MOX fuel assemblies at its MELOX plant in France.MOX Fuel AssemblyMHI has previously supplied 57 MOX fuel assemblies to Japanese utilities, and will supply high-quality MOX fuel by leveraging its past experience and technical capability. MOX fuel will enable Kyushu to utilize plutonium extracted by reprocessing spent fuel, and MHI will contribute to steady promotion of Kyushu's "Plu-Thermal" plan(2) through the supply of MOX fuel.(1) MOX (Mixed Oxide Fuel) is nuclear fuel made of plutonium extracted by reprocessing of spent fuel, and uranium.(2) The "Plu-Thermal" plan is to utilize MOX fuel in light water reactors.About MHI GroupMitsubishi Heavy Industries (MHI) Group is one of the world’s leading industrial groups, spanning energy, smart infrastructure, industrial machinery, aerospace and defense. MHI Group combines cutting-edge technology with deep experience to deliver innovative, integrated solutions that help to realize a carbon neutral world, improve the quality of life and ensure a safer world. For more information, please visit www.mhi.com or follow our insights and stories on spectra.mhi.com. Copyright 2024 JCN Newswire via SeaPRwire.com.
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CITIC Telecom CPC Propels ‘+AI to AI+’ ACN Newswire

CITIC Telecom CPC Propels ‘+AI to AI+’

HONG KONG, Oct 18, 2024 - (ACN Newswire via SeaPRwire.com) - CITIC Telecom International CPC Limited (“CITIC Telecom CPC”), a wholly-owned subsidiary of CITIC Telecom International Holdings Limited (SEHK: 1883) is at the forefront of AI+ innovation era, enabling dual empowerment of technology and data, and fostering a new business model of intelligence and innovation across industries. CITIC Telecom CPC has further unleashed multiple AI+ projects powered by “AI+ Cloud, Network, Security” framework, the integration of AI technology with big data analytics and security capabilities, and vital customer experience, fueling innovative AI+ applications across industries to reshape the Intelligence Operation Journey of enterprises.CITIC Telecom CPC collaborates with partners to co-create AI+ EcosystemFrom “Technology Empowerment”(+AI) to “Data Empowerment” (AI+)AI has become a cornerstone in today’s business landscape. As a leading Global-Local Intelligent DICT Service Partner, CITIC Telecom CPC fully embraces the global digitalization era and proactively deploys the visionary “ICT-MiiND” framework. This framework seamlessly integrates an “innovative” technology stack, the power of algorithms and big data into the ICT service platform, spanning across “Cloud, Network, Security” and bolstering the element of “intelligence” through cutting-edge AI technology and AIOps modules. CITIC Telecom CPC believes in the transformative power of AI+, actively enhances the in-depth integration of AI across various industries, driving innovative projects from focusing on "Big Data Modelling" to "Small-Scale Scenario implementation". CITIC Telecom CPC has not only deployed extensive resources in AI technologies, but also deeply integrated generative AI applications across the full-chain technology modules, evolving from Technology Empowerment (+AI) to Data Empowerment (AI+), ushering in a new era driven by AI algorithms and big data. AI+ covers diverse AI technologies and applications, integrating big data platforms with small-scale scenario models. This approach covers data collection, storage, governance and mining through deep algorithms, machine learning, and intelligent analysis, to develop a range of intelligent applications and AI+ solutions. Tailored to meet enterprise needs, it provides a one-stop service from business transformation to strategic analysis, efficiently fulfilling enterprise requirements.“CITIC Telecom CPC strives to integrate large AI models with diverse AI+ applications in small-scale scenarios, empowering customers to advance intelligent capabilities, unlocking a realm of new possibilities,” said Mr. Brook Wong, CEO of CITIC Telecom CPCMr. Brook Wong, Chief Executive Officer of CITIC Telecom CPC, said, “Striding from +AI to AI+, CITIC Telecom CPC pioneers AI technologies with a steadfast commitment to ‘Innovation Never Stops', continuously optimizes “Cloud, Network, Intelligence, Security” "solutions, and accelerates the development of intelligence-enabled industries. We actively dedicate various resources and collaborate with partners to co-create a prosperous AI+ ecosystem, enrich technical infrastructure, lead our team and the industry towards a generative AI era driven by large language models, AI technologies, data and intelligent analysis. We strive to integrate large AI models with diverse AI+ applications in small-scale scenarios, empowering customers to advance intelligent capabilities, unlocking a realm of new possibilities.”Transformative AI+ Solutions Generate New Driving Force for Data & Security ApplicationsCITIC Telecom CPC stands at the forefront of AI technology. With decades of ICT experience and industry expertise, its data science and innovation teams are propelling AI innovations with cutting-edge algorithms and deep learning techniques, unlocking data value and accumulating a range of generative AI applications for enterprises. The team has developed a series of award-winning and groundbreaking AI+ solutions such as the newly-launched AI Databank and AI Pentest, driving operational efficiency and cost savings for enterprises.AI Databank – Powering Big Data with Fast, Accurate & Actionable Insights on a Single PlatformAI Databank integrates tremendous data from various business systems, collecting a wide array of internal and external information (such as CRM and ERP). Utilizing generative AI technology, enhanced by deep learning and big data training, it enables efficient data management and real-time report generation. Users can interact with the platform to quickly retrieve data and multiple real-time data charts through dialog-based data queries, empowering data-driven decision making. AI Databank also analyzes current and historical data to build forecast models, helping companies in future planning.AI Pentest – Redefining Vulnerability Assessment with Proactive, Secure and Intelligent AutomationCITIC Telecom CPC has successfully led the Security Operations Center (SOC) to enter into a new AI-driven era since the launch of "TrustCSI™ 3.0" cybersecurity solution at the end of last year. The newly-launched AI Pentest plays a key role in the security portfolio. It is a lightweight solution powered by unique AI-driven bypass techniques to expose WAF vulnerabilities, enabling automated routine task scheduling to simplify the assessment of internal network asset and empower enterprises to keep pace with the rapidly changing IT environment. AI Pentest functions as an AI robot cleaner which automatically operates 24x7, helping enterprises identify key vulnerabilities in the network and establish a robust defense against potential threats.CITIC Telecom CPC's AI+ solutions have been implemented in various industries to foster integration of diverse AI+ applicationsAI+ Reshapes Industries with New Scenarios & Business ValuesCITIC Telecom CPC's AI+ solutions have been implemented in various industries to foster integration of diverse AI+ applications, assisting customers in incorporating generative AI technology, deep learning and data applications, empowering digital transformation for enterprises including:- AI+TelecommunicationsCITIC Telecom CPC leverages AI+ innovation capabilities to create a "Network and Information Security Threats Identification Algorithm Model". Leveraging Natural Language Processing (NLP), algorithm models and innovative technical architecture, an "AI+ telecommunications industry" application platform is created. The platform uses large AI security industry models to learn and identify scams as well as the patterns and characteristics of fraudulent calls. A repetitive learning and training cycle, integrated deep learning capability, on a large amount of known scams and fraudulent calls data is conducted to automatically identify new suspicious calls in the network immediately, greatly improving the accuracy of analysis and interception, and generating values for the society.Use case: Developed by CITIC Telecom, “AI+ Digital and Intelligent Cross-border Mobile Network Security Service Platform” project has won multiple distinguished awards in the market. The project utilizes Voice/Signaling/SMS firewall interception to help major telecommunications service providers, mobile service operators and enterprise sector to enable real-time alerts and interception of illegal and fraudulent Voice/SMS messages. The cloud-based platform can be utilized in local and cross-border cross-network scenarios to identify SMS messages from international countries to mainland China and inter-country communications. The solution effectively helps citizens identify registered SMS senders to stop fraudsters from sending scam SMS messages masquerading as other companies or organizations.- AI+ ManufacturingAs the global manufacturing industry is booming rapidly, the integration with different new technologies is accelerating. Powered by AI, enterprises actively deploy multiple AI tools, diverse application scenarios and big data to build an innovative digital and intelligence ecosystem. Industry chain not only enhances production efficiency and quality, but also responds to changes efficiently through digital planning and intelligent analysis, and also devises more precise future operations plans. AI-driven data security solutions provide enterprises with instant responses to security threats,enhanced data and cyber security, secure and intelligent manufacturing environment, elevating intelligent production to a new level.Use case: CITIC Dicastal, the first lighthouse factory in the global aluminum wheel industry, paved the way for its transformation journey with pivotal support from CITIC Telecom CPC and its subsidiary China Entercom in establishing a secure, efficient and fast data highway. This initiative enabled seamless connectivity among its global factories and significantly enhanced its digital and intelligent operational management capabilities. Leveraging its industry expertise, insights and technical knowledge, CITIC Telecom CPC’s Innovation team empowered CITIC Dicastal to overcome networking and security challenges across various application scenarios, including AI-driven manufacturing, process optimization, R&D design, operational decision-making, green and low-carbon initiatives, facilitating to build a “Vertical Industry Big Model of Aluminum Automobile Parts”, enhancing production efficiency and intelligence. CITIC Telecom CPC’s “AI+ Cloud, Network, Security” not only empowers the intelligent enhancement of CITIC Dicastal's entire industry chain but also reinforces its "AI+ Security" capabilities, refines real-time response alerts and develops interconnection across global factories while effectively monitoring information security threats. These initiatives strengthen the cornerstone of information security, forging a new era for the “Lighthouse Factory”. - AI+ AutomobileDemand forecasting is the most important part of the digital and intelligent transformation of an enterprise's supply chain. CITIC Telecom CPC's "Intelligent Order Demand Forecasting Solution" utilizes AI technology to predict complex and fragmented materials, improving the forecasting accuracy of order demand for vehicle models, and dynamically adjusting materials and production capacity planning.Use case: Headquartered in Europe, a world-renowned automobile parts supplier operates in 29 countries and regions, and serves various well-known automobile brands around the world. CITIC Telecom CPC’s "Intelligent Order Forecast Solution" enables customers to increase forecast accuracy to over 80%, optimize supply chain management, and achieve cost reduction and efficiency improvement.- AI+ RetailThe retail industry is undergoing a large-scale implementation of AI applications. CITIC Telecom CPC's “Cloud, Network, Intelligence, Security” integrated platform help enterprises build a secure, efficient and flexible digital infrastructure, enhance network transmission, information security, cloud computing resources and AI platform capabilities through dynamic perception, predictions and intelligent alerts for networks and applications. Harnessing AI technology and data analysis, we facilitate enterprises in expediting their digital transformation. By enhancing traditional workflow designs with scenario templates like customer service management, R&D evaluation, and marketing reports, strategically utilize big data to reinvent business to seize market opportunities.Use case: A world-renowned cosmetics retail brand has been committed to scientific research and innovation for many years. CITIC Telecom CPC's “AI+ Cloud, Network, Security” integrated platform helps to build a secure, efficient and flexible digital infrastructure. The dynamic perception of networks and applications, predictions and intelligent alerts for networks and applications assist the cosmetics retail brand to realize the values of “In Shanghai, For China, and Connect the World" to meet the needs of consumers in mainland China and around the world.To know more information aboutFrom “Technology Empowerment” (+AI) to “Data Empowerment” (AI+),please visit https://www.citictel-cpc.com/en-hk/ict-miindAbout CITIC Telecom CPCWe are CITIC Telecom International CPC Limited (“CITIC Telecom CPC”), a wholly-owned subsidiary of CITIC Telecom International Holdings Limited (SEHK: 1883), serving multinational enterprises the world over by addressing their specific ICT requirements with highly scalable tailored solutions built upon our flagship technology suites, comprising TrueCONNECT™ private network solutions, TrustCSI™ information security solutions, DataHOUSE™ cloud data center solutions, and SmartCLOUD™ cloud computing solutions.With the motto “Innovation Never Stops,” we leverage innovative technologies to boost technology empowerment (+AI). Embracing AI, AR, Big Data, IoT, and other cutting-edge emerging technologies we aim to unlock technical potential. By integrating deep learning and intelligent data analysis technologies, we transform these technologies into data empowerment (AI+) generative applications, reshaping the Intelligence Operation Journey of enterprises.With our Global-Local capabilities, we are committed to providing our customers with one-stop-shop ICT solutions with superior quality. Having a worldwide footprint across nearly 160 countries and regions, including Asia, Europe and America, Africa, the Middle East, and Central Asia, our global network resources connect nearly 170 points of presence (POPs), 60+ SDWAN gateways, 21 Cloud service centers, 30+ data centers, and three dedicated 24x7 Security Operations Centers (SOCs). We are certified with a series of international certifications, including SD-WAN Ready, ISO 9001, 14001, 20000, 27001, and 27017, to ensure our services compliance with international standards and resources for enterprises. We offer local professional services, superior delivery capabilities as well as exceptional customer experience and best practices through our global presence and extensive industry know-how, becoming a leading integrated intelligent ICT service provider to enterprise customers.For more information, please visit www.citictel-cpc.comMedia Contacts:Catherine YuenCITIC Telecom CPC(852) 2170 7536Email: catherine.yuen@citictel-cpc.com Copyright 2024 ACN Newswire via SeaPRwire.com.
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Bagaimana kapal karam Uluburun ditemui secara tidak sengaja oleh seorang penyelam span Berita

Bagaimana kapal karam Uluburun ditemui secara tidak sengaja oleh seorang penyelam span

(SeaPRwire) - Pada tahun 1982, penemuan yang dibuat oleh seorang penyelam span mendorong ahli arkeologi untuk melakukan 22,000 kali menyelam untuk menggali kawasan kapal karam Uluburun. Kapal karam berusia 3,300 tahun itu pada mulanya ditemui oleh seorang penyelam di luar pantai berhampiran Kaş, menurut laman web Institute of Nautical Archaeology (INA), yang menggali kawasan itu. Kawasan itu digali oleh ahli arkeologi bawah air selama sebelas musim antara tahun 1984 dan 1994, menurut sumber tersebut. Terdapat banyak cabaran yang datang dengan arkeologi bawah air, termasuk tetapi tidak terhad kepada isu-isu berkaitan dengan memelihara objek di dalam air, serta cuaca, pasang surut dan hidupan laut yang berpotensi menimbulkan halangan tambahan. Penggalian kapal karam itu berlangsung selama 10 tahun, dan jumlah masa kerja adalah tiga hingga empat bulan, menurut laman web Muzium Arkeologi Bawah Air Bodrum, yang mempunyai serta yang lain yang terkenal. Ahli arkeologi menggali lebih daripada 18,000 buah artifak dari Zaman Gangsa Akhir semasa penggalian mereka, menurut sumber tersebut. Kapal itu membawa muatan termasuk ingot tembaga dan timah, serta tembikar dan barang mewah seperti bekas gading ukiran dan barang kemas yang diperbuat daripada emas dan batu separuh berharga, menurut INA. Kebanyakan barang kemas yang ditemui di tapak itu adalah kepingan Mesir, seperti loket berbentuk cakera emas, manik faience, manik cangkerang telur burung unta, gelang perak dan banyak lagi, menurut laman web Muzium Arkeologi Bawah Air Bodrum.Objek lain yang berada di atas kapal termasuk gading gajah, serta senjata, barang dapur, pemberat imbangan dan alat muzik, menurut INA. Terdapat 24 sauh batu yang juga ditemui, dengan hanya sedikit bahagian lambung kapal yang rosak yang masih ada dari kapal yang diperbuat daripada kayu cedar, menurut Muzium Arkeologi Bawah Air Bodrum.Kapal karam Uluburun adalah salah satu yang telah dan penyelidik, serta diterokai oleh pelancong di Muzium Arkeologi Bawah Air Bodrum di Turki.Muzium ini mempunyai pameran yang didedikasikan untuk kapal karam Uluburun, yang memaparkan representasi kapal yang sebenar.Kapal itu berukuran 15 meter panjang menurut muzium dan dipercayai telah menyimpan sehingga 20 tan muatan. Artikel ini disediakan oleh pembekal kandungan pihak ketiga. SeaPRwire (https://www.seaprwire.com/) tidak memberi sebarang waranti atau perwakilan berkaitan dengannya. Sektor: Top Story, Berita Harian SeaPRwire menyampaikan edaran siaran akhbar secara masa nyata untuk syarikat dan institusi, mencapai lebih daripada 6,500 kedai media, 86,000 penyunting dan wartawan, dan 3.5 juta desktop profesional di seluruh 90 negara. SeaPRwire menyokong pengedaran siaran akhbar dalam bahasa Inggeris, Korea, Jepun, Arab, Cina Ringkas, Cina Tradisional, Vietnam, Thai, Indonesia, Melayu, Jerman, Rusia, Perancis, Sepanyol, Portugis dan bahasa-bahasa lain.
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Hamas Akui Kerugian ‘Sangat Menyakitkan dan Menyedihkan’ Selepas Video Israel Tunjukkan Teroris Sinwar Sebentar Sebelum Kematiannya

(SeaPRwire) - Hamas pada hari Jumaat mengakui telah mengalami kerugian yang "sangat menyakitkan dan menyedihkan" berikutan tentera Israel telah mengeluarkan video dron baharu yang merakam detik-detik terakhir hayat pengganas itu.Rakaman yang diambil daripada Sinwar yang cedera menunjukkan dia sedang membaling papan kayu ke arah dron yang sedang memantau kerosakan di dalam bangunan yang disasarkan oleh di Rafah, menurut Jurucakap IDF Laksamana Muda Daniel Hagari. Sinwar kemudiannya ditemui mati dengan senapang dan hampir $11,000 dalam simpanannya, tambahnya."Ya, sangat menyakitkan dan menyedihkan untuk kehilangan orang yang disayangi, terutamanya pemimpin luar biasa seperti kita, tetapi yang pasti ialah kita akhirnya akan menang; inilah hasilnya bagi semua orang yang berjuang untuk kebebasan mereka," kata pegawai kanan Hamas Basem Naim pada hari Jumaat."Nampaknya Israel percaya bahawa membunuh pemimpin kita bermakna berakhirnya gerakan kita dan perjuangan rakyat Palestin. Mereka boleh percaya apa sahaja yang mereka mahu, dan ini bukan kali pertama mereka berkata begitu," sambungnya. Naim menambah bahawa meskipun pembunuhan terdahulu pengasas Hamas, komander pertama sayap ketenteraannya, kumpulan pengganas itu "setiap kali menjadi lebih kuat dan lebih popular, dan pemimpin-pemimpin ini menjadi ikon untuk generasi akan datang untuk meneruskan perjalanan menuju Palestin yang bebas.""Hamas adalah gerakan pembebasan yang dipimpin oleh orang yang mencari kebebasan dan maruah, dan ini tidak dapat dihapuskan," katanya juga. telah berkata pada hari Khamis berikutan pengumuman kematian Sinwar di selatan Semenanjung Gaza bahawa "Hamas tidak akan lagi memerintah Gaza" dan "inilah permulaan hari selepas Hamas, dan ini adalah peluang untuk anda, penduduk Gaza, untuk akhirnya bebas daripada tirani mereka."Laporan Radio Tentera Israel berkata pada hari Khamis bahawa Sinwar terbunuh dalam pertempuran dengan tentera Israel. Tentera itu telah mengesan suspek pengganas di Gaza dan melepaskan tembakan sebelum individu-individu itu melarikan diri ke dalam bangunan, menurut laporan itu. Ia menambah bahawa sebuah kereta kebal kemudiannya melepaskan tembakan ke bangunan itu, menyebabkannya runtuh.Apabila tentera itu masuk untuk memeriksa kesan runtuhan, mereka menemui tiga mayat - salah satunya akhirnya dikenal pasti sebagai Sinwar.Artikel ini disediakan oleh pembekal kandungan pihak ketiga. SeaPRwire (https://www.seaprwire.com/) tidak memberi sebarang waranti atau perwakilan berkaitan dengannya. Sektor: Top Story, Berita Harian SeaPRwire menyampaikan edaran siaran akhbar secara masa nyata untuk syarikat dan institusi, mencapai lebih daripada 6,500 kedai media, 86,000 penyunting dan wartawan, dan 3.5 juta desktop profesional di seluruh 90 negara. SeaPRwire menyokong pengedaran siaran akhbar dalam bahasa Inggeris, Korea, Jepun, Arab, Cina Ringkas, Cina Tradisional, Vietnam, Thai, Indonesia, Melayu, Jerman, Rusia, Perancis, Sepanyol, Portugis dan bahasa-bahasa lain.
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The 15th Turkish-Arab Economic Forum (TAFF 2024) took place at the Four Seasons Bosphorus Hotel in Istanbul ACN Newswire

The 15th Turkish-Arab Economic Forum (TAFF 2024) took place at the Four Seasons Bosphorus Hotel in Istanbul

ISTANBUL, October 18, 2024 - (ACN Newswire via SeaPRwire.com) - The 15th Turkish-Arab Economic Forum (TAFF 2024), aimed at deepening relations between Turkiye and the Gulf countries and defining joint strategies for the region, took place yesterday in Istanbul.The Forum saw the attendance of many key figures from the Gulf countries, including Kuwait's Minister of Finance Noora Suleiman Salem Al-Fassam, Iraq's Minister of Finance Taif Sami Mohammed, Egypt's Deputy Minister of Finance Ahmed Kouchouk, Tunisia's Minister of Economy and Planning Samir Abdelhafidh, Libya's Minister of Finance Dr Kalid Al-Mabrouk, President of the Turkish Investment Fund Baghdad Amreyev, Secretary General of the Egyptian Federation of Arab Chambers Dr Khaled Hanafy, Regional Director of the Saudi International Finance Corporation Fawaz Bilbeisi, Director of the World Bank GCC Cooperation Safaa El Tayeb El-Kogali, Partner at the UK's DWF Solomon Ebere, Board Member of the Qatar Chamber Mohamed Bin Ahmed Al Obaidly, and Vice President of International Business Development of the United Arab Emirates Khalid Al Marzooqi.Turkiye's Minister of Treasury and Finance Mehmet Simsek evaluated global and regional strategies.In his speech at the 15th Turkish-Arab Economic Forum, Minister of Treasury and Finance Mehmet Simsek highlighted the decline in inflation and the slowdown in monetary policies. He emphasized that global trade will continue in November, pointing out that while there are challenges, there are also opportunities in this process. Mehmet Simsek further noted that he expects an increase in cooperation across various sectors, emphasizing that partnerships in energy, manufacturing, technology, and machinery are crucial for realizing the region's potential and he expressed his support for diversification strategies.Dr. Erkan Kork stated that Turkiye and the Gulf countries could build a shared future.Speaking at the 15th Turkish-Arab Economic Forum, Dr. Erkan Kork, Chairman of the Board of BankPozitif, highlighted that the participating countries share the same geography, history, and values, and emphasized that joint steps would be stronger and more effective. He noted that building a shared future with the available know-how, technology, and investments is vital for unlocking the region's potential.BankPozitif Chairman Dr Erkan Kork at the 15th Turkish Arab Economic ForumExpressing pride in Turkiye's positioning as a fintech hub, Dr Erkan Kork predicted that Turkiye would play a leading role on the global stage in various fields in the near future. He also stressed the importance of forums, fairs and events like this for fostering relationships between the business world and governments of different countries.In his speech, Dr Erkan Kork pointed out that Turkiye is in a very strong position in terms of innovation and information technology, noting that while processing times in many sectors in Europe are long, they are much shorter in Turkiye. Dr. Erkan Kork also highlighted Turkiye's high level of competitiveness in recent years.At the forum, which had a high participation rate, Fatih Karahan, Governor of the Central Bank of the Republic of Turkiye, Burak Dagloglu, Member of the Board of Directors of the Turkiye Wealth Fund, and Rfat Hisarckloglu, President of the Union of Chambers and Commodity Exchanges of Turkiye, were also among the speakers.Source: BankPozitif, https://www.bankpozitif.com.trSait Inanc, +90533 722 49 69, info@bankpozitif.com.tr* This press release is issued through EuropeNewswire.Net (www.europenewswire.net) and distributed by EmailWire (www.emailwire.com) – the gloabal newswire that provide Press Release Distribution with Guaranteed Results™. Copyright 2024 ACN Newswire via SeaPRwire.com.
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Everest Medicines’ Stock Price Rises by 20% as Profit Potential Drives Valuation Recovery

HONG KONG, Oct 18, 2024 - (ACN Newswire via SeaPRwire.com) - Everest Medicines (1952.HK) closed today with a 20.46% increase, hitting a high of HKD 28.6. The company's stock price has been steadily rising since the release of its interim results, with today's trading volume reaching HKD 291 million. Market updates show that BOCOM International released a report assigning an 'outperform' rating to the Chinese pharmaceutical sector, with Everest Medicines being one of the key recommended stocks.Recently, the Hong Kong government released a policy address with numerous measures aimed at attracting overseas capital to Hong Kong, which has been a positive driver for the Hong Kong stock market. Additionally, negative sentiment in the innovative drug sector is gradually fading, and the market is now focusing on companies with profit potential and valuation recovery resilience.According to Everest Medicines' 2024 interim financial report, the company saw a significant revenue increase in the first half of the year, reaching RMB 302 million, representing a 158% growth compared to the second half of last year, marking the first time the company has achieved commercial profitability. The company's core products, Nefecon® and XERAVA® (the world's first-in-class fluorocycline antibiotic), have already been commercialized, with three products expected to be launched by the end of the year. In terms of innovative research and development, Everest Medicines owns an mRNA platform with full intellectual property rights and global benefits, dedicated to developing both preventive and therapeutic mRNA products. The company expects to achieve full-year sales of RMB 700 million by 2024 and aims to break even by the end of 2025.As BOCOM International released a report, it highlighted that innovative drug companies with abundant short-term catalysts, strong profit growth potential, or clear break-even timelines, along with significant valuation recovery potential, are worth close attention. Investors are also advised to focus on small and mid-sized innovative pharmaceutical companies whose market value diverges significantly from their fundamentals. These companies are expected to experience a strong rebound as liquidity improves.Over the past two months, Everest Medicines' stock has risen by over 65%. Recently, the unexpected adjustments in domestic monetary policy further energized capital markets. The continuous rise in both Hong Kong and mainland Chinese stock markets highlights the innovative drug sector as a key area of focus, given its long-term valuation bottoming and significant growth potential, making it a highly attractive investment in this market rally. Copyright 2024 ACN Newswire via SeaPRwire.com.
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Hitachi Receives Order for 56 Elevators and Escalators for CRC The Flagship in Noida, India JCN Newswire

Hitachi Receives Order for 56 Elevators and Escalators for CRC The Flagship in Noida, India

TOKYO, Oct 18, 2024 - (JCN Newswire via SeaPRwire.com) - Hitachi, Ltd. (TSE: 6501; hereafter Hitachi), today announced that Hitachi Building Systems Co., Ltd. (hereafter Hitachi Building Systems) and Hitachi Lift India Pvt. Ltd. (hereafter Hitachi Lift India), a subsidiary of Hitachi, Ltd. which operates sales, installation, and maintenance of elevators and escalators in India, successfully secured an order for 56 units of elevators and escalators from CRC Group for CRC The Flagship in Noida, Uttar Pradesh, India. Theproject is one of the most prestigious commercial projects in Noida.The order consists of 44 elevators including high-speed elevators with a rated speed of 180 or 150 m/min, 12 escalators and a destination floor reservation system that efficiently allocates elevator cars. The elevators have anearthquake emergency operation system that detects an earthquake and stops the elevator quickly on the closest floorso that passengers can get out without being stuck in it. These features provide users with safety, security, and comfort.Masaya Sakakibara, Managing Director, Hitachi Lift India said “We are honored to be involved in this prestigious project for the Noida district. Our aim is to contribute to the safe, secure and comfortable transportation for all usersand development of the city by offering our high-quality products and services. We will continue to commit to the improvement of India’s society and the well-being of its people.”Bharat Kaushal, Corporate Officer, Hitachi, Ltd. and Managing Director, Hitachi India said “Hitachi India Pvt. Ltd. (hereafter Hitachi India)’s burgeoning partnership with India for over nine decades is growing at an unprecedented pace. As India accelerates its voyage to become one of the leading economies in the world by not only empowering its citizens, but also by building a world class infrastructure to enhance quality of life for billions. Hitachi Lift India is an integral partner of India’s transformational journey and CRC Group has been instrumental in further strengthening the resilient infrastructural landscape of the nation. We are overwhelmed to collaborate with CRC Group that marks a significant milestone in our commitment to further enhancing the urban infrastructure in India. This collaboration not only represents a strategic alignment between two leading organizations but also underscores our shared vision of innovation and excellence in ensuring India takes a giant leap forward for setting unparalleled architectural benchmarks, building a sustainable society. With our exemplary yet varied bouquet of solutions including urban mobility, energy, IT, payments, e- Education and e-Healthcare, Hitachi India is chartering an ambitious and progressive vision for building an ecosystem that further supports the mission of offering best in class technology for India and for the World.”By undertaking this project, Hitachi Lift India aims to enhance its presence in the premium market and commit to the further business growth in India.Outline of CRC The FlagshipCRC The Flagship is a 223,000 square-meter business hub mainly consisting of 4 towers and a retail building. It offers office spaces, retail shops, and premium services apartments with various facilities such as a co-working space, an auditorium, and even a putting golf course.The project also has the greenery with more than 20% of its whole area, achieving climate- friendly infrastructure with pre-certified platinum rating by Indian Green Building Council.Closely located to the Noida–Greater Noida Expressway, it takes approximately 35 minutes from Noida InternationalAirport, being constructed at present and to be the one of the biggest international airports in India as an alternative to Indira Gandhi International Airport.Outline of CRC GroupCRC Group is a highly respected developer in the NCR region of India known for its premium projects. The Group is dedicated to enhancing the standards in the real estate industry by introducing the finest buildings, which have beenand will continue to be full of perfection and excellence.Hitachi's Elevators and Escalators Business in IndiaIndia's new installation market for elevators and escalators exceeds 67,000 units in fiscal year 2023, making it the world's second-largest market that is expected to grow 6-7% per year.Hitachi established Hitachi Lift India in January 2008 and began full-scale operations in the elevator and escalatormarket. Since then, it has secured many orders and has been engaged in installing and maintaining its products,including high-speed elevators for luxury residences, hotels, and offices. Hitachi Lift India currently operates in all majorcities in India, such as Delhi NCR, Mumbai, Bengaluru, Chennai, Pune, Hyderabad, and Ahmedabad.For more information, visit www.hitachi.com/New/cnews/month/2024/10/241017.pdf. Website of Hitachi Lift India: www.hitachi-lift.co.in/Website of Hitachi Elevators and Escalators: www.hitachi.com/businesses/elevator/Hitachi Building Systems Brand Channel: www.youtube.com/channel/UCfOgxcLRk3NHm2WrqHeQ6MAAbout Hitachi, Ltd.Hitachi drives Social Innovation Business, creating a sustainable society through the use of data and technology. We solve customers' and society's challenges with Lumada solutions leveraging IT, OT (Operational Technology) and products. Hitachi operates under the 3 business sectors of “Digital Systems & Services” – supporting our customers’ digital transformation; “Green Energy & Mobility” – contributing to a decarbonized society through energy and railwaysystems, and “Connective Industries” – connecting products through digital technology to provide solutions in variousindustries. Driven by Digital, Green, and Innovation, we aim for growth through co-creation with our customers. The company’s revenues as 3 sectors for fiscal year 2023 (ended March 31, 2024) totaled 8,564.3 billion yen, with 573 consolidated subsidiaries and approximately 270,000 employees worldwide. For more information on Hitachi, please visit the company's website at www.hitachi.com. Copyright 2024 JCN Newswire via SeaPRwire.com.
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China Medical System: First Ruxolitinib Cream’s Prescriptions for Vitiligo Issued in the Greater Bay Area ACN Newswire

China Medical System: First Ruxolitinib Cream’s Prescriptions for Vitiligo Issued in the Greater Bay Area

SHENZHEN, CHINA, Oct 18, 2024 - (ACN Newswire via SeaPRwire.com) - China Medical System Holdings Limited (the “Group” or “CMS”) is pleased to announce that on 18 October, the first batch of prescriptions of ruxolitinib phosphate cream (the “ruxolitinib cream” or the “Product”) for qualified vitiligo patients were issued in the Greater Bay Area, at Zhongshan Chen Xinghai Hospital of Integrated Traditional Chinese and Western Medicine, Foshan Fosun Chancheng Hospital, and Dongguan Songshan Lake Tungwah Hospital. The Product’s new drug application (NDA) was approved by the Pharmaceutical Administration Bureau (ISAF) of Macau on 11 April 2024, and subsequently the Product was approved by the Guangdong Provincial Medical Products Administration on August 19 through the "Hong Kong and Macau Medicine and Equipment Connect" policy, which officially introduced ruxolitinib cream for the treatment of non-segmental vitiligo with facial involvement in adults and adolescents from 12 years of age, providing a novel treatment option for patients with relevant indication into designated medical institutions in the Mainland of Greater Bay Area.In addition, on 24 September, the NDA for vitiligo indication of ruxolitinib cream has been accepted by the National Medical Products Administration of China (NMPA). In accordance with the relevant regulations of the drug real-world data application pilot program in the Hainan Boao Lecheng International Medical Tourism Pilot Zone (the “Pilot Zone”), CMS has conducted a real-world study on ruxolitinib cream in China. The results have shown positive efficacy, which is consistent with the key outcomes of global pivotal clinical studies. All secondary efficacy endpoints showed a trend of benefit consistent with the primary efficacy endpoint, and the treatment effect for vitiligo continued to improve with longer treatment duration. Meanwhile, through the safety monitoring data of the Pilot Zone, no new safety events have been identified. Adverse events mostly had severity levels of grade 1 or 2. No adverse event (AE) leading to discontinuation or withdrawal, and no serious adverse event (SAE) related to the study drug occurred.If the Product is successfully approved for marketing in Mainland China, it will be the first prescription drug approved by NMPA for repigmentation in vitiligo, bringing this novel treatment hopes for Chinese vitiligo patients.Furthermore, on 12 August 2023, the Product was approved by Hainan Medical Products Administration for Urgent Clinical Import, and officially became available to applicable patients in the Pilot Zone on August 18, for the topical treatment of non-segmental vitiligo in adults and adolescents aged 12 and above with facial involvement. Benefiting from the Early and Pilot Implementation Policy granted by the state to Hainan Free Trade Port and the Pilot Zone, patients with vitiligo in China can apply for the Product in Boao Super Hospital first and receive treatment from the expert team. As of 30 June 2024, more than 3,200 patients have been treated with ruxolitinib cream in Boao Super Hospital.CMS has always been patient-oriented and innovation-driven based on clinical needs, continuously striving to improve drug accessibility. Benefited from the "Hong Kong and Macau Medicine and Equipment Connect" policy, ruxolitinib cream was approved for use in the Greater Bay Area and completed its first batch of prescriptions, shortening the time difference for Chinese vitiligo patients to use innovative drug and benefiting more domestic patients. Looking forward to the future, the Group will continuously strive to meet the unmet needs of Chinese patients, continuously explore novel drugs with international quality, and efficiently promote products’ clinical development and commercialization, so as to bring more quality pharmaceutical products through differentiated innovation-breakthrough, to safeguard the health and life-quality of patients.About ruxolitinib creamRuxolitinib cream (Opzelura), a novel cream formulation of Incyte’s selective JAK1/JAK2 inhibitor ruxolitinib, is approved by the U.S. Food & Drug Administration for the topical treatment of nonsegmental vitiligo in patients 12 years of age and older. As of now, it is the first and only treatment for repigmentation approved for use in the United States[1]. Ruxolitinib cream (Opzelura) is also approved in the U.S. for the topical short-term and non-continuous chronic treatment of mild to moderate atopic dermatitis (AD) in non-immunocompromised patients 12 years of age and older whose disease is not adequately controlled with topical prescription therapies, or when those therapies are not advisable[2]. In Europe, ruxolitinib cream (Opzelura) is approved for the treatment of non-segmental vitiligo with facial involvement in adults and adolescents from 12 years of age[3].On 2 December 2022, the Group through a subsidiary of the Company, a dermatology medical aesthetic company (“CMS Skinhealth”) entered into a Collaboration and License Agreement (the “License Agreement”) with Incyte for topical formulations of ruxolitinib for the treatment of autoimmune and inflammatory dermatology diseases. In accordance with the License Agreement, the Group through CMS Skinhealth received an exclusive license to develop, register and commercialize the Product in Mainland China, Hong Kong Special Administrative Region, Macau Special Administrative Region, Taiwan Region and eleven Southeast Asian countries (Indonesia, Philippines, Vietnam, Thailand, Myanmar, Malaysia, Cambodia, Laos, Singapore, Timor-Leste and Brunei Darussalam) (the “Territory”) and a non-exclusive license to manufacture the Product in the Territory. The License Agreement commenced on its effective date and has a royalty term of ten years from the date of the commercial sale of the Product in the Territory (the “Royalty Term”). Upon the expiration of the Royalty Term, the License Agreement may be renewed for a period of ten years thereafter (the “Initial Extended Royalty Term”) as per certain conditions defined in the License Agreement. Upon the expiration of the Initial Extended Royalty Term, the License Agreement may be extended for a period otherwise agreed by both sides as per certain conditions defined in the License Agreement.Incyte has worldwide rights for the development and commercialization of the Product, marketed in the United States and Europe as Opzelura®. Opzelura and the Opzelura logo are registered trademarks of Incyte.About vitiligoVitiligo is a chronic autoimmune disease characterized by depigmentation of the skin, which results from the loss of pigment-producing cells known as melanocytes. It is estimated that there are approximately 14 million vitiligo patients in China[4]. Non-segmental vitiligo patients account for approximately 85% of them. Topical corticosteroids (TCS) and calcineurin inhibitors (CI) are used off-label for non-segmental vitiligo, however, these therapies have clinical deficiencies with long-term adverse reactions of long-term treatment or limited efficacy[5,6].About CMSCMS is a platform company linking pharmaceutical innovation and commercialization with strong product lifecycle management capability, dedicated to providing competitive products and services to meet unmet medical needs.CMS focuses on the global first-in-class (FIC) and best-in-class (BIC) innovative products, and efficiently promotes the clinical research, development and commercialization of innovative products, enabling the continuous transformation of scientific research into clinical practices to benefit patients.CMS deeply engages in several specialty therapeutic fields, and has developed proven commercialization capabilities, extensive networks and expert resources, resulting in leading academic and market positions for its major marketed products. CMS continues to promote the in-depth development of its advantageous specialty fields and expand business boundaries. While strengthening the competitiveness of the cardio-cerebrovascular/gastroenterology business, CMS independently operates its dermatology and medical aesthetics business, and ophthalmology business, aiming to gain leading positions in specialty therapeutic fields, whilst enhancing the scale and efficiency. At the same time, CMS has expanded its business territory to the Southeast Asian market, striving to become a "bridgehead" for global pharmaceutical companies to enter the Southeast Asian market, further escorting the sustainable and healthy development of the Group.Reference:1. Drug approval information can be found on the FDA official website, as follows: https://www.fda.gov/drugs/news-events-human-drugs/fda-approves-topical-treatment-addressing-repigmentation-vitiligo-patients-aged-12-and-older2. Drug approval information can be found on the Incyte official website, as follows: https://investor.incyte.com/news-releases/news-release-details/incyte-announces-us-fda-approval-opzeluratm-ruxolitinib-cream3. Drug approval information can be found on the EMA official website, as follows: https://www.ema.europa.eu/en/medicines/human/EPAR/opzelura4. Ezzedine K, Eleftheriadou V, Whitton M, van Geel N. Vitiligo. Lancet. 2015;386(9988):74-84. doi:10.1016/S0140-6736(14)60763-75. Consensus on the diagnosis and treatment of vitiligo (2021 version)6. Kubelis-López DE, Zapata-Salazar NA, Said-Fernández SL, Sánchez-Domínguez CN, Salinas-Santander MA, Martínez-Rodríguez HG, Vázquez-Martínez OT, Wollina U, Lotti T, Ocampo-Candiani J. Updates and new medical treatments for vitiligo (Review). Exp Ther Med. 2021 Aug;22(2):797. doi: 10.3892/etm.2021.10229. Epub 2021 May 25. PMID: 34093753; PMCID: PMC8170669.CMS Disclaimer and Forward-Looking StatementsThis press release is not intended to promote any products to you and is not for advertising purposes. This press release does not recommend any drugs, medical devices and/or indications. If you want to know more about the diagnosis and treatment of specific diseases, please follow the opinions or guidance of your doctor or other medical and health professionals. Any treatment-related decisions made by healthcare professionals should be based on the patient’s specific circumstances and in accordance with the drug package insert.This press release which has been prepared by CMS does not constitute any offer or invitation to purchase or subscribe for any securities, and shall not form the basis for or be relied on in connection with any contract or binding commitment whatsoever. This press release has been prepared by CMS based on information and data which it considers reliable, but CMS makes no representation or warranty, express or implied, whatsoever, and no reliance shall be placed on, the truth, accuracy, completeness, fairness and reasonableness of the contents of this press release. Certain matters discussed in this press release may contain statements regarding the Group’s market opportunity and business prospects that are individually and collectively forward-looking statements. Such forward-looking statements are not guarantees of future performance and are subject to known and unknown risks, uncertainties and assumptions that are difficult to predict. Any forward-looking statements and projections made by third parties included in this press release are not adopted by the Group and the Company is not responsible for such third-party statements and projections.Media ContactChina Medical System Holdings Ltd.CMS Investor RelationsWebsite: https://web.cms.net.cn/en/home/Source: China Medical System Holdings Ltd. Copyright 2024 ACN Newswire via SeaPRwire.com.
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Eco Expo Asia opens at AsiaWorld-Expo in late October ACN Newswire

Eco Expo Asia opens at AsiaWorld-Expo in late October

- Eco Expo Asia is expected to attract over 300 exhibitors from 11 countries and regions with new exhibitor groups from Anhui Province and Norway- The Expo will feature three focal points: New Energy, Waste Management and Circular Economy, and ESG-related Services, in pursuit of achieving the dual carbon goals- Government officials, industry experts and business leaders from various countries and regions, including Belt and Road countries will attend the Eco Asia Conference- Talks and workshops on the last day of the Expo (2 November) will be open to the public for freeHONG KONG, Oct 17, 2024 - (ACN Newswire via SeaPRwire.com) - Eco Expo Asia 2024, jointly organised by the Hong Kong Trade Development Council (HKTDC) and Messe Frankfurt (HK) Ltd and co-organised by the Environment and Ecology Bureau of the Government of the Hong Kong Special Administrative Region (HKSAR), will be held at AsiaWorld-Expo from 30 October to 2 November. The last day of the event will be open to the public for free.To extend the sourcing journey, exhibitors and buyers worldwide can connect via the Click2Match virtual business matching platform from 23 October to 9 November.HKTDC Assistant Executive Director Jenny Koo said: "In the face of climate change, countries and regions have been actively propelling carbon reduction policies and sustainable development. China, for instance, set carbon reduction and neutrality goals in 2020 and has been advocating the development of new quality productive forces. The Hong Kong SAR Government is also committed to achieving carbon neutrality before 2050, and the development of related industries has become increasingly diversified, laying a strong foundation for Hong Kong’s sustainable development. Themed Fostering Green Innovations for Carbon Neutrality, the 19th edition of Eco Expo Asia will bring together international exhibitors and industry professionals to showcase cutting-edge innovations and technologies that aim to achieve dual carbon goals.”Speaking at the press conference, the Deputy Director of the Environmental Protection Department of the HKSAR Government, Fong Kin-wa, expressed: "We hope the Eco Expo Asia could share with visitors and exhibitors from around the world, including Belt and Road countries and ASEAN countries, the latest green innovation for achieving carbon neutrality, with a view to promoting exchange and cooperation between governments and trade sectors on boosting green & low-carbon transformation, achieving sustainable development, and leading Hong Kong towards carbon neutrality.”Converging international exhibitors and government officials at Eco Expo AsiaThis year’s Expo is expected to attract over 300 exhibitors from 11 countries and regions including Mainland China, Hong Kong, Macao, Taiwan, Singapore, Germany, Finland, Norway, the Netherlands, the United States and Canada. Several provinces and cities from Mainland China will form pavilions, including the return of Guangzhou and Shenzhen. The Anhui Pavilion will debut with technologies focused on air quality, water treatment and quality management as well as new energy materials and equipment. Supported by Innovation Norway, the debut group participation from Norway will showcase technologies for water quality management and waste treatment.The Eco Asia Conference, held during the first three days of the exhibition, will provide a platform for government officials, industry experts and business leaders from various countries and regions to discuss key trends, including energy projections, green building technologies and the circular economy. The conference is supported by the Ministry of Ecology and Environment, National Development and Reform Commission, and Ministry of Industry and Information Technology of the People’s Republic of China. Officials from Belt and Road countries, including Malaysia, Laos, Saudi Arabia, Myanmar, Brunei and Vietnam will also attend the conference.Three focal points in pursuit of dual carbon goalsTo achieve dual carbon goals, the development of green energy and green transportation has become a global trend. New energy is a focus of this year’s exhibition and many innovative new energy-related products and technologies will be featured. For example, Hong Kong’s first hydrogen fuel cell street-cleaning vehicle will be showcased at the booth hosted by the Environment and Ecology Bureau in conjunction with other HKSAR government units.The Inner Mongolia Pavilion will showcase cutting-edge solutions in environmental protection, ecological restoration and new energy. Innovative technical solutions, such as hydrogen purification systems and carbon capture and storage equipment, will be highlighted at the Canada Pavilion. In the Green Transportation zone, GMI Motors Ltd and first-time exhibitor Xiamen Golden Dragon Bus Co. Ltd will present a variety of electric vehicles. Chun Yang International (HK) Company Ltd will demonstrate fast charging and mini wall-mounted EV chargers catering to different needs.Waste Management and Circular Economy is a second focal point of the Expo, with exhibitor Smart Farming HK Ltd showcasing fish feed made from food waste and a sustainable fish farming concept. First-time exhibitor Nanda (Hong Kong) Technology Corporation Ltd will feature a food waste biodegradation machine that can process up to 36,000 kg of food waste per day.The Sustainable Restaurant Awards 2024, the first of its kind in Hong Kong's F&B industry to recognise restaurants based on their carbon footprint, will be presented on the third day of the Expo.The third focal point of the Expo is ESG-related services which is experiencing strong demand. Several world-leading certification and consultancy companies will exhibit for the first time, including SGS Hong Kong Ltd, Intertek Testing Services Hong Kong Ltd, TUV Rheinland Hong Kong Ltd and BSI Pacific Ltd to present their testing and certification services as well as ESG consulting and training programmes. ESG AI, an innovative tool launched by China Energy Conservation & Environmental Protection (Hong Kong) Investment Co. Ltd, makes use of big data analysis and other technologies to generate regulatory-compliant ESG reports in one click.Nurturing talent to inject fresh energyEco Expo Asia has long been a platform for start-ups to showcase their latest innovations. Hong Kong Science and Technology Parks Corporation will showcase products and technologies from 10 start-ups related to green transport, circular economy and energy efficiency.In the popular Start-up Zone, exhibitor Ezygreenpak Ltd will demonstrate its patented water-soluble non-woven packaging material that can be completely dissolved in 90°C hot water without leaving any harmful residue. BSF Innovation Ltd's organic green building powder, consisting of fibre and calcium extracted from insect shells and food waste, can be blended with traditional building materials to make eco-bricks, reducing the manufacturing process carbon emissions by around 40%.A series of seminars and workshops on Public DayTo encourage residents to adopt green living practices, talks and workshops will be held on the last day of the Expo (2 November), which are free and open to the public. A highlight will be the Dialogue with the Secretary for Environment and Ecology for school students. Experts will share their strategies and experience in tackling extreme weather. The public can also participate in a variety of green workshops and shop for green products at Green Mart.Photo download: https://bit.ly/3BWSrpjJenny Koo, Assistant Executive Director of the HKTDC, introduced Eco Expo Asia highlights at the press conference. She said Hong Kong’s environmental-related industries were expanding in diversity, establishing the groundwork for the city’s sustainable development.The Chief Executive’s 2024 Policy Address released yesterday emphasises the need to promote the development of new energy and expand the electric vehicle charging network. Ms Koo stated that the HKTDC has been committed to promoting sustainable development in the business sector. In October, the HKTDC will work closely with the Environmental and Ecology Bureau to hold Eco Expo Asia, and provide support services and sourcing platforms to assist industry players in promoting and sourcing green products and solutions. In addition to Eco Expo Asia, the HKTDC aims to facilitate international connections through large-scale flagship events, promoting Hong Kong's role as an international centre for green finance and green technologyJenny Koo, Assistant Executive Director, HKTDC (centre); Fong Kin-wa, Deputy Director of the Environmental Protection Department of the HKSAR Government (left), and Judy Cheung, Deputy General Manager, Messe Frankfurt (HK) Ltd (right), attended the press conferenceGMI Motors Ltd displayed a brand-new, 32-seater electric bus with a large capacity batteryStart-up Ezygreenpak Ltd demonstrated its innovative water-soluble non-woven packaging material that can completely dissolve in 90°C hot waterTen companies resident at Hong Kong Science and Technology Parks Corporation sites will take part in the exhibition. Growgreen Ltd and One Energy (HK) Ltd showcased products related to circular economy and green transportation at the press conferenceSmart Farming HK Ltd introduced food waste recycled feed and fish farming sustainabilityWebsiteEco Expo Asia: www.ecoexpoasia.comMedia enquiriesPlease contact the HKTDC’s Communications and Public Affairs Department:Stanley SoTel: (852) 2584 4049Email: stanley.hp.so@hktdc.orgClayton Lauw Tel: (852) 2584 4472 Email: clayton.y.lauw@hktdc.orgThe HKTDC’s Media Room: http://mediaroom.hktdc.com/enAbout HKTDCThe Hong Kong Trade Development Council (HKTDC) is a statutory body established in 1966 to promote, assist and develop Hong Kong's trade. With 50 offices globally, including 13 in Mainland China, the HKTDC promotes Hong Kong as a two-way global investment and business hub. The HKTDC organises international exhibitions, conferences, and business missions to create business opportunities for companies, particularly small and medium-sized enterprises (SMEs), in the mainland and international markets. The HKTDC also provides up-to-date market insights and product information via research reports and digital news channels. For more information, please visit: www.hktdc.com/aboutus.Background information on Messe FrankfurtThe Messe Frankfurt Group is one of the world’s leading trade fair, congress and event organisers with their own exhibition grounds. With a workforce of some 2,160 people at its headquarters in Frankfurt am Main and in 28 subsidiaries, it organises events around the world. Group sales in financial year 2022 were around €454 million. We serve our customers’ business interests efficiently within the framework of our Fairs & Events, Locations and Services business fields. One of Messe Frankfurt’s key strengths is its powerful and closely knit global sales network, which covers around 180 countries in all regions of the world. Our comprehensive range of services – both onsite and online – ensures that customers worldwide enjoy consistently high quality and flexibility when planning, organising and running their events. We are using our digital expertise to develop new business models. The wide range of services includes renting exhibition grounds, trade fair construction and marketing, personnel and food services. Sustainability is a central pillar of our corporate strategy. Here, we strike a healthy balance between ecological and economic interests, social responsibility and diversity.For more information, please visit our website at: www.messefrankfurt.com/sustainability. With its headquarters in Frankfurt am Main, the company is owned by the City of Frankfurt (60 percent) and the State of Hesse (40 percent). For more information, please visit our website at: www.messefrankfurt.com Copyright 2024 ACN Newswire via SeaPRwire.com.
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Pembuangan Sinwar dari medan perang adalah ‘penting’, membuka peluang gencatan senjata, kata Jabatan Negara

(SeaPRwire) - The pada hari Khamis berkata pembunuhan pemimpin Hamas Yahya Sinwar oleh tentera Israel telah memberikan "peluang" untuk gencatan senjata berpotensi dan berakhirnya perang selama setahun. Jurucakap Jabatan Negara Matthew Miller berkata sehingga , "tidak ada jalan untuk mengakhiri perang ini kerana Sinwar telah enggan berbincang mengenai pembebasan tebusan.""Kami kini melihat peluang dengan dia telah dikeluarkan dari medan perang, dikeluarkan dari kepimpinan Hamas. Kami mahu merebut peluang itu," kata Miller. Sinwar adalah arkitek utama serangan 7 Oktober 2023, di mana menyerbu Israel, membunuh hampir 1,200 orang dan menculik 250 orang lain dalam serangan yang mengejutkan negara itu. Sehingga Oktober 2024, pejuang Hamas masih memegang sekitar 100 tebusan. Pasukan Israel memuji kematian Sinwar sebagai kemenangan besar, tetapi Perdana Menteri Benjamin Netanyahu berjanji bahawa negaranya akan terus berjuang sehingga semua tebusan dibebaskan. Dia berkata pasukan Israel akan mengawal Gaza cukup lama untuk memastikan Hamas tidak mempersenjatai semula.Tidak jelas siapa yang akan menggantikan Sinwar. Walaupun kematiannya adalah tamparan besar kepada Hamas, kumpulan itu telah membuktikan ketahanan terhadap kehilangan pemimpinnya pada masa lalu. "Satu perkara yang kita tahu pasti ialah dunia adalah tempat yang lebih baik dengan Sinwar tiada di dalamnya, dan ia memberi kita peluang yang tidak kita miliki selagi dia masih memanggil tembakan untuk Hamas," kata Miller. "Sekarang apakah maksudnya, kita perlu tunggu dan lihat dalam beberapa hari akan datang."Dalam 12 bulan pertempuran, pasukan Israel telah membunuh lebih daripada 42,000 warga Palestin dan memusnahkan sebahagian besar Semenanjung Gaza. Angka-angka tersebut berasal dari Kementerian Kesihatan Gaza yang dikawal Hamas, yang tidak membezakan antara orang awam dan pejuang tetapi mengatakan separuh daripada mereka yang terbunuh adalah wanita dan kanak-kanak. Artikel ini disediakan oleh pembekal kandungan pihak ketiga. SeaPRwire (https://www.seaprwire.com/) tidak memberi sebarang waranti atau perwakilan berkaitan dengannya. Sektor: Top Story, Berita Harian SeaPRwire menyampaikan edaran siaran akhbar secara masa nyata untuk syarikat dan institusi, mencapai lebih daripada 6,500 kedai media, 86,000 penyunting dan wartawan, dan 3.5 juta desktop profesional di seluruh 90 negara. SeaPRwire menyokong pengedaran siaran akhbar dalam bahasa Inggeris, Korea, Jepun, Arab, Cina Ringkas, Cina Tradisional, Vietnam, Thai, Indonesia, Melayu, Jerman, Rusia, Perancis, Sepanyol, Portugis dan bahasa-bahasa lain.
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MHI Thermal Systems Receives Order for Large-scale Centrifugal Chillers from Empower for its District Cooling Plants in Dubai, UAE JCN Newswire

MHI Thermal Systems Receives Order for Large-scale Centrifugal Chillers from Empower for its District Cooling Plants in Dubai, UAE

TOKYO, Oct 18, 2024 - (JCN Newswire via SeaPRwire.com) - Mitsubishi Heavy Industries Thermal Systems, Ltd. (MHI Thermal Systems), a part of Mitsubishi Heavy Industries (MHI) Group, has signed a new agreement with Emirates Central Cooling Systems Corporation PJSC (Empower), the world's largest district cooling services provider(Note1), to supply large-scale centrifugal chillers to Empower's District Cooling plants in Dubai, UAE.CEO H.E. Ahmad Bin Shafar and President Ito at the Signing CeremonyUnder the agreement, MHI Thermal Systems will supply 18 advanced chillers that will be ready for delivery from the beginning of 2025 for an aggregate cooling capacity of 56,250 refrigeration tons (RT) (Note2). They will be used in three District Cooling System (DCS) plants that Empower operates and will supply chilled water for cooling to residential, commercial, healthcare, educational, and multi-use projects. The agreement also includes a provision allowing Empower to increase the order up to 31 December 2024, potentially increasing the total capacity to 100,000 RT.MHI Thermal Systems has previously received an order for large-scale centrifugal chillers from Empower in 2021. The latest contract was received in recognition of the excellent chilling efficiency and environmental performance of MHI Thermal Systems chillers, as well as the operational performance and after-sales service from the previous order. Delivery is scheduled to begin sequentially from 2025, bringing the total number of chillers delivered to Empower to at least 46 units. The use of DCS is part of the Dubai government's long-term strategies, aiming to achieve savings of at least 30% by 2030 and 50% by 2050 in electricity, water and transport fuel consumption.MHI Thermal Systems and Empower held a contract signing ceremony in Dubai on October 8, attended by Empower CEO H.E. Ahmad Bin Shafar, and MHI Thermal Systems President Yoshihiro Ito.President Ito said: "We are proud that Empower has highly evaluated the performance and the quality of the after-sales service of the units previously delivered, and has once more chosen MHI Thermal Systems' chillers for these latest projects. We will continue improving energy efficiency while continuously enhancing operational and production effectiveness. We will continue implementing our advanced solutions to Empower's DCS plants so that our partnership will also contribute to the Dubai and the UAE's carbon emissions reduction strategy."Ahmad Bin Shafar emphasized that this deal offers both parties a significant opportunity to advance the district cooling sector and accelerate efforts toward a carbon-free future through energy-efficient solutions. He noted that these solutions reduce environmental impact and pave the way for a more sustainable tomorrow. Bin Shafar also highlighted that the agreement supports Empower's goal of upgrading its plants with innovative technologies that promote efficient, energy-saving production processes, aligning with the company's environmental and societal objectives and its commitment to safeguarding resources for future generations.Empower is responsible for more than 80% of Dubai's district cooling capacity, supplying chilled water for cooling from 87 district cooling plants, making it the world's largest district cooling services provider.MHI Thermal Systems, as a part of MHI Group, will continue to respond to customer needs and contribute to the realization of a carbon-neutral world through the supply of energy-efficient centrifugal chillers.(1) In terms of connected capacity(2) 1 refrigeration ton = approx. 3.516 kWAbout MHI GroupMitsubishi Heavy Industries (MHI) Group is one of the world’s leading industrial groups, spanning energy, smart infrastructure, industrial machinery, aerospace and defense. MHI Group combines cutting-edge technology with deep experience to deliver innovative, integrated solutions that help to realize a carbon neutral world, improve the quality of life and ensure a safer world. For more information, please visit www.mhi.com or follow our insights and stories on spectra.mhi.com. Copyright 2024 JCN Newswire via SeaPRwire.com.
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Fujitsu and Teikyo University begin joint research on UX platform for promotion of lifestyle improvement using XR, spatial computing, and generative AI JCN Newswire

Fujitsu and Teikyo University begin joint research on UX platform for promotion of lifestyle improvement using XR, spatial computing, and generative AI

TOKYO, Oct 18, 2024 - (JCN Newswire via SeaPRwire.com) - Fujitsu and the Okinaga Research Institute at Teikyo University announced that, as of today, they will begin a full-scale joint research project for the development of a user experience (UX) platform. This platform will help to improve health consciousness and healthcare literacy by increasing patients’ understanding of their internal condition through the use of digital technology, such as extended reality (XR) and spatial computing (1).In this research project, Fujitsu and the Okinaga Research Institute will use XR and spatial computing to recreate a patient's internal anatomy in a virtual space, enhancing their understanding of the locations where health issues may arise. The two parties will examine how this visualization can foster health consciousness, behavioral change, and improved patient outcomes. The technology will be used in interviews with patients who have been advised to improve their lifestyle based on health check results. In addition, the two parties will also create an AI healthcare supporter avatar with generative AI technology to follow up with patients and will examine its effect on improving patient healthcare literacy.BackgroundIn recent years, lifestyle-related diseases have increased among both the elderly and younger populations. Preventing serious illness through lifestyle improvements is expected to reduce the national healthcare burden, improve corporate labor productivity, and enhance individual quality of life. Consequently, the Japanese Ministry of Health, Labour and Welfare requires health insurance societies to devise and implement data health plans. From this, effective improvements are being promoted through the plan-do-check-act (PDCA) cycle. In this cycle, data from the results of health checkups retained by health insurance societies and medical treatment bills are used to analyze the relationship between the data obtained from the medical examination and diseases to improve patient’s lifestyle.Improving lifestyles requires not only the support of healthcare providers but also a fundamental shift in individual mindset.In October 2022, Fujitsu and the Okinaga Research Institute started conducting research to eliminate the communication gap between doctors and patients by using XR, spatial computing, and generative AI in informed consent. This research led to the development such as virtual internal body models generated from patients’ biological data and technology for an AI medical supporter avatar. This research forms the basis of this latest project.Roles of Both Parties:1. Fujitsu- Conducting design research (2) with related parties and experts to identify hinderances to people’s awareness of true lifestyle improvement- Creating UX/UI scenarios for people to autonomously improve their lifestyles- Providing development support for an initial prototype, suggest improvements, and conduct a demonstration test with the prototype2. Okinaga Research Institute:- Providing medical expertise- Sharing visualization expertise in the area of medicine- Developing an initial prototype that uses organ dataFuture PlansBased on the results of this joint research project, Fujitsu and Teikyo University will contribute to improving people’s well-being and solving societal issues related to health by preventing lifestyle-related diseases through the societal implementation of health guidance that utilizes digital technology.(1) Spatial computing: A technology that seamlessly integrates physical and digital spaces, enabling people to interactively control information within that space.(2) Design research: Research with the aim of designing products and services from the user’s point of view. In this research, various information is collected and organized to identify potential customer needs and discover new issues and value.About FujitsuFujitsu’s purpose is to make the world more sustainable by building trust in society through innovation. As the digital transformation partner of choice for customers in over 100 countries, our 124,000 employees work to resolve some of the greatest challenges facing humanity. Our range of services and solutions draw on five key technologies: Computing, Networks, AI, Data & Security, and Converging Technologies, which we bring together to deliver sustainability transformation. Fujitsu Limited (TSE:6702) reported consolidated revenues of 3.7 trillion yen (US$26 billion) for the fiscal year ended March 31, 2024 and remains the top digital services company in Japan by market share. Find out more: www.fujitsu.com.Press Contacts:Fujitsu LimitedPublic and Investor Relations DivisionInquiriesTeikyo UniversityHeadquarters Public Relations SectionInquiries Copyright 2024 JCN Newswire via SeaPRwire.com.
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MarTech Menerajui WebEngage Mendapat Momentum di Asia Pasifik

- Syarikat menyasarkan untuk merevolusikan penglibatan pelanggan dalam perniagaan B2C melalui strategi yang dipacu dan pengekalan rundingan - Momentum di Asia Pasifik disaksikan di sebalik keputusan tambahan yang terbukti dihasilkan untuk perniagaan ikonik seperti PFI Mega Life, Unilever, Arabian Oud dan PasarPolis serta banyak lagi - WebEngage telah menubuhkan pasukan khas perunding pertumbuhan dan pakar domain yang berpangkalan di Jakarta, Indonesia serta hubungan rakan kongsi yang kukuh dan maju di rantau ini termasuk Malaysia, Vietnam, Thailand dan Filipina Jakarta, Indonesia & Mumbai, India, Oct 15, 2024 - (ACN/NewsVoir) - Menurut laporan IDC, pelaburan AI Generatif di rantau Asia Pasifik (APAC) dijangka mencecah sehingga $110 bilion dalam tempoh empat tahun akan datang dengan cerapan dan penyelesaian yang dikuasakan oleh AI yang dijangka bakal mengubah masa depan perniagaan. Dengan ketersediaan rantau ini dalam memacu kemajuan teknologi, WebEngage, peneraju global dalam perundingan pengekalan dan penglibatan pelanggan, telah mengumumkan pengembangannya dalam pasaran Asia Pasifik pada hari ini. Syarikat tersebut menyasarkan untuk merevolusikan cara perniagaan di rantau APAC berinteraksi bersama pelanggan mereka dengan menawarkan set alatan komprehensif bagi memperkasakan pemasar untuk mencipta kempen tersendiri dan berkesan. Dengan matlamat yang besar bagi mencapai pertumbuhan 5 kali ganda menjelang 2027, langkah strategik ini bertujuan untuk memanfaatkan ekosistem permulaan yang berkembang pesat di rantau ini dan perniagaan warisan yang mengutamakan digital. WebEngage telah ditetapkan untuk meningkatkan pengalaman pelanggan dan memacu pertumbuhan yang mampan dalam APAC bagi jenama B2C dengan strategi yang lebih maju, kuasa AI serta berfungsi dengan baik. [caption id="" align="aligncenter" width="1000"] Imej perkhidmatan penuh yang ditawarkan oleh WebEngage kepada pelanggan[/caption] Hetarth Patel, Naib Presiden Pasaran Pertumbuhan (MEA, Amerika, APAC), WebEngage, menekankan bahawa kepentingan APAC sebagai pasaran utama bagi syarikat, memandangkan peningkatan permintaan untuk penyelesaian penglibatan pelanggan yang didorong oleh ekonomi digital dinamik rantau ini. Beliau berkata, “Dalam landskap kompetitif hari ini, perniagaan semakin menyedari keperluan penglibatan pelanggan yang diperibadikan secara berlebihan untuk memupuk kesetiaan dan meningkatkan Nilai Sepanjang Hayat Pelanggan. CDP yang dikuasakan oleh AI kami, enjin dan suite penglibatan telah menghasilkan peningkatan pendapatan dan margin yang konsisten pada perniagaan di pasaran Asia Pasifik bagi pelanggan iaitu PFI Mega Life, Unilever, Arabian Oud dan PasarPolis serta lain-lain. Kami menyasarkan untuk menjadi rakan kongsi platform automasi pemasaran dan penglibatan pelanggan yang paling diutamakan bagi perniagaan di Asia Pasifik menjelang tahun 2027. Kami juga sedang membina sebuah ekosistem yang kukuh dalam kalangan rakan kongsi seperti Penyepadu Sistem Global, Rumah Perunding dan Agensi Pemasaran Digital di seluruh Indonesia, Malaysia, Vietnam, Thailand dan Filipina.” Landskap terkini mendedahkan jurang yang ketara dalam penggunaan AI generatif dalam kalangan perniagaan, mengehadkan keupayaan mereka untuk mencipta kandungan hiper-peribadi dan menjalankan kajian. "Matlamat kami adalah untuk mengubah naratif tersebut," kata Patel. "Dengan menyepadukan keupayaan AI kami akan terbukti dapat diaplikasikan dalam industri dan sub-industri tertentu, perniagaan boleh mencapai tahap kreativiti dan kecekapan yang baharu." WebEngage diaplikasikan dalam strategi pertumbuhan jangka panjang di APAC, memfokuskan pada inovasi bagi menangani keperluan unik pasaran. Ia berdiri kukuh bersama pelanggan terkemuka seperti PFI Mega Life, PasarPolis TyrAds, QBFoods dan MedsGo, merangkumi industri termasuk e-dagang, runcit, kewangan dan lain-lain. Pelanggan WebEngage telah memperlihatkan peningkatan luar biasa dalam pendapatan dan margin sehingga 40% merentas industri. WebEngage merupakan sebuah platform automasi pemasaran terkemuka yang memberikan penyelesaian analisis pemasaran yang bersesuaian. Dengan memanfaatkan data pihak pertama dan carian yang tepat. WebEngage telah melebarkan sayap sekurang-kurangnya lebih 800 buah jenama di seluruh India, Timur Tengah & Afrika, Amerika Latin dan Asia Tenggara dalam membangunkan strategi penglibatan yang diperibadikan yang disesuaikan dengan keperluan keunikan pelanggan mereka. Untuk maklumat lanjut tentang WebEngage, layari laman web: https://webengage.com/ Tentang WebEngage: WebEngage membantu menaikkan jenama pengguna dan mengekalkan pelanggan mereka ke arah peningkatan nilai pembelian dan ROI pemasaran. Susunan produk termasuk data pelanggan dan platform analitik yang teguh – menggabungkan data tanpa halangan, tahap penglibatan terbaik dalam pengkelasan dengan pembinaan berbagai saluran dan enjin pemperibadian yang membantu meningkatkan penukaran bagi semua saluran, termasuk web dan aplikasi mudah alih. Kedudukan #1 secara konsisten merentasi di semua platform ulasan mengenai kemudahan penggunaan dan kelengkapan platform, WebEngage digunakan lebih 800 buah jenama di seluruh pasaran India, Timur Tengah & Afrika, Amerika Latin dan Asia Tenggara. Ia merentasi senarai industri E-Commerce & Travel, Edtech, BFSI & Fintech termasuk jenama seperti Unilever, Walmart, Airtel, Myntra, L'Occitane, Cipla, Reliance General Insurance, Tata Mutual Fund, Unacademy, Pepperfry, GoIbibo, Adani One, PFI Mega Life, PasarPolis, Wego, Groww, Acko, Blackberrys serta banyak lagi. Untuk pertanyaan media APRW: Ferry Prihardiputra Hubungi: +62 817 526 8638 E-mel: ferry@aprw.asia WebEngage: Anand Vaidya Hubungi: +91 99300 58087 E-mel: anand.vaidya@webengage.com WebEngage: Simone Chhabda Hubungi: +91 9619128455 E-mel: simone.chhabda@webengage.com
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Bekas ketua keselamatan awam Mexico dihukum lebih 38 tahun, denda $2 juta kerana menerima rasuah daripada kartel Berita

Bekas ketua keselamatan awam Mexico dihukum lebih 38 tahun, denda $2 juta kerana menerima rasuah daripada kartel

(SeaPRwire) - Lelaki yang pernah dipuji sebagai arkitek perang Mexico terhadap kartel dadah dijatuhi hukuman lebih daripada 38 tahun penjara di Amerika Syarikat pada hari Rabu kerana menerima rasuah besar-besaran untuk membantu pengedar dadah.Genaro García Luna, bekas setiausaha keselamatan awam Mexico, didapati bersalah oleh juri New York pada tahun 2023 kerana menerima jutaan dolar rasuah untuk melindungi kartel yang sepatutnya dia lawan. Dia adalah pegawai kerajaan Mexico peringkat tertinggi yang disabitkan kesalahan di Amerika Syarikat.Pada sidang hukumannya di hadapan seorang hakim persekutuan di Brooklyn pada hari Rabu, García Luna terus menegaskan bahawa dia tidak bersalah dan berkata kes terhadapnya adalah berdasarkan maklumat palsu daripada penjenayah dan kerajaan Mexico."Saya mempunyai rasa hormat yang tinggi terhadap undang-undang," katanya dalam bahasa Sepanyol. "Saya tidak melakukan jenayah ini."García Luna, 56, memimpin sebelum dia berkhidmat dalam jawatan peringkat kabinet sebagai pegawai keselamatan tertinggi dari tahun 2006 hingga 2012 di bawah Presiden Felipe Calderón ketika itu. Pada masa itu, García Luna dipuji sebagai sekutu oleh Amerika Syarikat dalam perjuangannya menentang perdagangan dadah.Tetapi pendakwa raya Amerika Syarikat berkata sebagai balasan untuk berjuta-juta dolar, dia memberikan risikan mengenai siasatan terhadap kartel, maklumat mengenai geng saingan dan laluan selamat bagi sejumlah besar dadah.Selepas hukuman itu, Calderón berkata melalui platform sosial X bahawa dia menghormati keputusan mahkamah, tetapi dia tidak pernah mempunyai "bukti yang boleh disahkan" tentang kegiatan jenayah García Luna. Calderón berkata mengambil alih kartel "adalah salah satu keputusan paling sukar dalam hidup saya. Tetapi saya akan melakukannya lagi, kerana itu adalah perkara yang betul."Lebih awal di luar mahkamah, sekumpulan kira-kira 15 penunjuk perasaan meraikan keputusan itu. Ada yang memegang sepanduk yang bertulis, dalam bahasa Sepanyol, "Calderon tahu," manakala yang lain mengibarkan tanda-tanda yang mengecam parti politiknya.Pendakwa raya telah meminta hukuman seumur hidup. Peguam García Luna telah berhujah bahawa dia tidak sepatutnya menerima lebih daripada 20 tahun.Hakim Daerah Amerika Syarikat Brian Cogan berkata dia tidak terpengaruh dengan pujian masa lalu yang diterima García Luna untuk kerjanya dalam perang terhadap dadah."Itu adalah penyamaran anda," kata Cogan sebelum menjatuhkan hukuman. "Anda bersalah atas jenayah ini, tuan. Anda tidak boleh mempamerkan kata-kata ini dan berkata, 'Saya adalah pegawai polis tahun ini.'"Selain hukuman 38 tahun dan empat bulan, hakim menjatuhkan denda $2 juta.Semasa perbicaraan, foto-foto ditunjukkan García Luna bersalaman dengan bekas Presiden Barack Obama dan bercakap dengan bekas Setiausaha Negara Hillary Clinton dan bekas Senator John McCain.Tetapi pendakwa raya berkata García Luna secara rahsia memajukan konspirasi perdagangan dadah yang mengakibatkan kematian beribu-ribu rakyat Amerika dan Mexico. Dia memastikan bahawa pengedar dadah diberitahu terlebih dahulu tentang serbuan dan menyabotaj operasi polis yang sah yang bertujuan untuk menangkap pemimpin kartel, kata mereka.Pengedar dadah dapat menghantar lebih daripada 1 juta kilogram kokain melalui Mexico dan ke Amerika Syarikat menggunakan pesawat, kereta api, trak dan kapal selam ketika García Luna memegang jawatannya, kata pendakwa raya.Semasa perbicaraan bekas ketua Sinaloa Joaquin "El Chapo" Guzmán di mahkamah yang sama pada tahun 2018, seorang bekas ahli kartel bersaksi bahawa dia secara peribadi menyerahkan sekurang-kurangnya $6 juta dalam bayaran kepada García Luna dan bahawa anggota kartel bersetuju untuk mengumpulkan sehingga $50 juta untuk membayar perlindungannya."Dia membolehkan kartel. Dia melindungi kartel. Dia adalah kartel," kata Penolong Pendakwa Raya Amerika Syarikat Saritha Komatireddy kepada hakim pada hari Rabu.García Luna membolehkan sistem yang korup yang membolehkan untuk berkembang maju dan mengedarkan dadah yang membunuh berjuta-juta orang, tambahnya."Mungkin bukan tertuduh yang menarik pencetus, tetapi dia mempunyai darah di tangannya," kata Komatireddy.Pendakwa raya juga berkata García Luna berkomplot untuk membatalkan keputusan tahun lepas dengan cuba menyuap atau dengan rasuah meyakinkan beberapa banduan di Pusat Penahanan Metropolitan di Brooklyn untuk menyokong tuduhan palsu bahawa dua saksi kerajaan berkomunikasi melalui telefon bimbit seludup sebelum perbicaraan.Peguam García Luna, Cesar de Castro, berkata pembelaan berhasrat untuk merayu hukuman itu. Dia berkata anak guamnya adalah seseorang yang "telah berkhidmat untuk negaranya" dan kini telah kehilangan wang, reputasinya serta dasar yang dia perjuangkan di Mexico."Dia telah kehilangan hampir semuanya. Yang tinggal hanyalah keluarganya yang hebat," kata de Castro.Di Mexico, Presiden yang baru dilantik Claudia Sheinbaum secara ringkas mengulas mengenai kes tersebut pada hari Selasa, dengan berkata: "Masalah besar di sini adalah bagaimana seseorang yang dianugerahkan oleh agensi Amerika Syarikat, yang bekas Presiden Calderón berkata perkara-perkara yang baik tentang setiausaha keselamatannya, hari ini adalah tahanan di Amerika Syarikat kerana terbukti dia terikat kepada perdagangan dadah."Penangkapan dan sabitan García Luna menjadi senjata politik yang digunakan oleh parti pemerintah Sheinbaum dan pendahulunya, Andrés Manuel López Obrador, dalam pilihan raya presiden Mexico tahun ini menentang Parti Tindakan Nasional Calderón yang lemah. Mereka cuba menggambarkan García Luna sebagai poster kanak-kanak bagi rasuah dan Calderón sebagai orang yang bertanggungjawab atas peningkatan keganasan daripada perang dadah.López Obrador dan sekarang Sheinbaum berpaling dari konfrontasi langsung dengan kartel, sebaliknya memberi tumpuan kepada apa yang mereka anggap sebagai punca utama keganasan, seperti kemiskinan. Tetapi strategi baru itu gagal untuk mengurangkan tahap keganasan secara signifikan.López Obrador mempunyai reaksi yang sangat berbeza pada tahun 2020 ketika pihak berkuasa Amerika Syarikat menangkap bekas Menteri Pertahanan Mexico Salvador Cienfuegos kerana didakwa bersekongkol dengan kartel dadah. Dalam kes itu, López Obrador menuduh Pentadbiran Penguatkuasaan Dadah memalsukan bukti terhadap Cienfuegos dan memprotes sehingga kerajaan Amerika Syarikat menjatuhkan tuduhan tersebut. Dia dipulangkan ke Mexico, di mana dia segera dibersihkan dan dibebaskan.Artikel ini disediakan oleh pembekal kandungan pihak ketiga. SeaPRwire (https://www.seaprwire.com/) tidak memberi sebarang waranti atau perwakilan berkaitan dengannya. Sektor: Top Story, Berita Harian SeaPRwire menyampaikan edaran siaran akhbar secara masa nyata untuk syarikat dan institusi, mencapai lebih daripada 6,500 kedai media, 86,000 penyunting dan wartawan, dan 3.5 juta desktop profesional di seluruh 90 negara. SeaPRwire menyokong pengedaran siaran akhbar dalam bahasa Inggeris, Korea, Jepun, Arab, Cina Ringkas, Cina Tradisional, Vietnam, Thai, Indonesia, Melayu, Jerman, Rusia, Perancis, Sepanyol, Portugis dan bahasa-bahasa lain.
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TANAKA to Provide Medals Representing the Event Concept with a Design of Gently Curved Circular Expansion for the Tokyo Legacy Half Marathon 2024 JCN Newswire

TANAKA to Provide Medals Representing the Event Concept with a Design of Gently Curved Circular Expansion for the Tokyo Legacy Half Marathon 2024

TOKYO, Oct 18, 2024 - (JCN Newswire via SeaPRwire.com) - TANAKA Holdings Co., Ltd. (Head office: Chuo-ku Tokyo; Group CEO: Koichiro Tanaka) will provide and donate gold, silver, and bronze medals to the top three finishers in the half marathon (elite athletes) and elite para-athletes (wheelchair and visual impairment) award categories at the Tokyo Legacy Half Marathon 2024. The Tokyo Legacy Half Marathon 2024 is organized by the Tokyo Marathon Foundation and will be held on October 20, 2024.*If the top three finishers above have a guide runner, a medal will also be provided to the guide runner.Medals Using Gently Expanding Curves to Represent the Event’s ConceptThe medals were designed based on the concept of the Tokyo Legacy Half Marathon: "We want to expand the opportunity for everyone to run, including those who have never run before, and create an event in which anyone can participate." The front of the medal features the event title, Tokyo Legacy Half Marathon 2024, written in English, and incorporates the event logo, which uses a motif of gently curved circles expanding outward. This logo represents the Earth’s continuous rotation, honoring the dedication of the runners who have trained tirelessly for 365 days leading up to the event. Additionally, the design of the Earth is reduced to about half the size of the medal to symbolize the half marathon.On the back of the medal, Tokyo Legacy Half 2024 is inscribed in braille, along with the TANAKA Precious Metals logo, and the word "FINISHER" and the event date. The ribbon is designed with the event logo, which resembles a tapestry of interwoven lines representing each runner, volunteer, and spectator.About the Tokyo Legacy Half Marathon 2024The Tokyo Legacy Half Marathon 2024 is a public participation half marathon (21.0975 km) that is half the distance of the Tokyo Marathon (42.195 km). It was born from the desire to create a half marathon that would give the extraordinary experience of running to everyone. This year, the event’s tagline is "If it’s a half marathon, I can barely make it, Maybe." aiming to offer a race where a wide variety of runners can enjoy the streets of Tokyo at their own pace.(Official website of the event: https://legacyhalf.tokyo/en/ )Since the inaugural event in 2022, TANAKA Precious Metals has been producing the medals awarded at the Tokyo Legacy Half Marathon, and this will be their third time providing them. In addition to the Tokyo Legacy Half Marathon, the company has also produced winner’s medals for the Tokyo Marathon, supported the promotion of para-sports as an official partner of the Japanese Para-Sports Association (JPSA), and manufactured and sold the official commemorative medals for the 1964 Tokyo Olympics. TANAKA Precious Metals will continue to produce medals made of precious metals and support the promotion of sports with the aim of contributing to the realization of a prosperous society.Overview of the Tokyo Legacy Half Marathon 2024 MedalsWeight, size and materialGold Medal: approx. 55g; approx. 55mm in diameter and approx. 2.3mm thick; pure silver with gold platingSilver Medal: approx. 55g; approx. 55mm in diameter and approx. 2.3mm thick; pure silverBronze Medal: approx. 45g; approx. 55mm in diameter and approx. 2.3mm thick; pure copper Race Information of the Tokyo Legacy Half Marathon 2024OrganizerTokyo Marathon FoundationCo-organizersTokyo Metropolitan Government; JAAF (Japan Association of Athletics Federations); Tokyo Sports Association for the DisabledManaging OrganizationTokyo Athletics AssociationOperation SupportJapan Para AthleticsSupporting OrganizationsJapan Industrial Track & Field AssociationOfficial PartnersSky Co., Ltd.; Otsuka Pharmaceutical Co., Ltd.; New Balance Japan, Inc.; Tokyo Tatemono Co., Ltd.; KINTETSU INTERNATIONAL; Hisamitsu Pharmaceutical Co.,Inc.; Tokyo Kiraboshi Financial Group, Inc.; TANAKA Holdings Co., Ltd.; Rokko Butter, Co., Ltd.; Photocreate Co.,Ltd.; SEIKO GROUP CORPORATIONOfficial SuppliersNIHON KOHDEN CORPORATION; Porsche Japan K.K.DateSunday, October 20, 2024 (rain or shine)Start/Finish AreaJapan National Stadium (Kasumigaoka-machi, Shinjuku, Tokyo) About TANAKA Precious MetalsSince its foundation in 1885, TANAKA Precious Metals has built a portfolio of products to support a diversified range of business uses focused on precious metals. TANAKA is a leader in Japan regarding the volume of precious metals it handles. Over many years, TANAKA has manufactured and sold precious metal products for industry and provided precious metals in such forms as jewelry and assets. As precious metals specialists, all Group companies in Japan and worldwide collaborate on manufacturing, sales, and technology development to offer a full range of products and services. With 5,355 employees, the group’s consolidated net sales for the fiscal year ending December 2023, was 611.1 billion yen.TANAKA Holdings Websitehttps://www.tanaka.co.jp/english/Press inquiriesTANAKA Holdings Co., Ltd.https://tanaka-preciousmetals.com/en/inquiries-for-mediaPress Release: https://www.acnnewswire.com/docs/files/20241017.pdf Copyright 2024 JCN Newswire via SeaPRwire.com.
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Participation in the Multilateral System Remains High as Performance Drops, New Index Finds ACN Newswire

Participation in the Multilateral System Remains High as Performance Drops, New Index Finds

Washington, D.C., Oct 18, 2024 - (ACN Newswire via SeaPRwire.com) - Today marks the launch of the second edition of the Multilateralism Index from the International Peace Institute (IPI) and the Institute for Economics & Peace (IEP). The Index reveals that states remain engaged in the global multilateral system even as it increasingly struggles to address the crises it faces.Multilateralism Index 2024 ReportAn image of the front cover of the Multilateralism Index 2024 ReportKey resultsThe performance of the multilateral system declined across all five domains examined.Peace and security showed the steepest deterioration in performance, with the number of armed conflicts rising from 39 in 2013 to 55 in 2022.Climate action and human rights also saw significant declines in performance, despite increased engagement from member states.Participation in multilateral institutions has increased in most domains, even as performance has declined, indicating a shift from cooperation to contestation.Inclusivity improved across all domains, with steady growth in NGO engagement and women's representation in UN bodies.The Multilateralism Index 2024 presents a complex picture of global cooperation over the past decade, examining five crucial domains: Peace and Security, Human Rights, Climate Action, Public Health, and Trade. It reveals a contradiction: while participation in the multilateral system has largely held steady or even increased, its effectiveness in addressing global challenges has declined.Dr. Adam Lupel, IPI Vice President & COO said: "Over the past decade, we've witnessed a paradox in multilateralism. While participation in international institutions has largely held steady or even increased, the performance of the multilateral system in addressing global challenges has declined. This suggests a shift from cooperation to contestation at a time of transformation and rising global crises."The peace and security domain experienced the most significant deterioration in performance. Active armed conflicts increased from 39 in 2013 to 55 in 2022, with a notable rise in internationalized conflicts. The UN Security Council has seen more frequent use of the veto power, constraining its ability to respond to crises. However, states have not broadly pulled back from the UN peace and security architecture, and commitments in some areas, such as multilateral peacebuilding, have increased.Climate action presents another contradiction. Despite near-universal participation in the Paris Agreement and growing climate commitments, these commitments continue to fall short of necessary targets. Projections show an 8.8% increase in emissions by 2030, in stark contrast to the 43% decrease required to meet the critical 1.5°C target.The human rights domain exhibits a counterintuitive pattern. While engagement with UN human rights mechanisms has increased, global human rights protections have steadily declined. Most strikingly, members of the UN Human Rights Council consistently scored lower on human rights measures than the global average, indicating that many states are engaging less to advance human rights than to shape the direction of the system.Multilateral action on public health was significantly shaped by the COVID-19 pandemic, which reversed years of progress, particularly in areas such as childhood immunization. It also put the shortcomings of the global public health system in stark relief, spurring negotiations on an international pandemic agreement aimed at strengthening preparedness and response capabilities for future health crises.Trade is the one area where both performance and participation decreased. The paralysis of global trade negotiations and breakdown in adherence to global trade rules signal a shift away from multilateral approaches. This trend, combined with growing geopolitical tensions, creates challenges for global economic cooperation.Steve Killelea, Founder & Executive Chairman of IEP, commented: "The Multilateralism Index 2024 reveals a challenging trend: while engagement in global institutions has increased, their effectiveness has declined across key areas. There is a need to revitalize our multilateral system to address today's complex challenges."Despite these challenges, the Index highlights positive developments, particularly in the area of inclusivity. NGO engagement with the UN system has grown, and women's representation has increased across many UN bodies. However, the Global South remains underrepresented in many areas, suggesting that geographic inclusivity remains a work in progress.As the world contends with interconnected crises, from conflict to climate change, the Multilateralism Index 2024 provides valuable insights into the current state of global cooperation. It underscores the need for thoughtful reform to ensure that multilateral institutions can effectively address the complex challenges of the 21st century.Contact InformationMike KoslowskiIEP Senior Communications Advisormkoslowski@economicsandpeace.org+61418410531Related FilesMultilateralism Index 2024 - Full Press Release (1)Multilateralism Index 2024 - Full Press Release (1)SOURCE: International Peace Institute Copyright 2024 ACN Newswire via SeaPRwire.com.
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DPC Dash – Domino’s Pizza China Drives Sales and Profit Growth and Optimizes Shareholder Structure

HONG KONG, Oct 18, 2024 - (ACN Newswire via SeaPRwire.com) - As recent economic stimulus measures by the government of China boost consumer confidence, and propel a rally in domestic stock markets, consumption stocks have been leading the surge, closing strong in the third quarter of 2024 strong. DPC Dash – Domino’s Pizza China, ("DPC Dash" or the "Company") (1405.HK), Domino's Pizza's exclusive master franchisee in the China Mainland, the Hong Kong Special Administrative Region of China, and the Macau Special Administrative Region of China, has further optimized shareholder structure to deliver long-term and significant value to shareholders.In the third quarter of 2024, the Company announced its inclusion in the Hong Kong Hang Seng Composite Index and the Shanghai-Hong Kong and Shenzhen-Hong Kong Stock Connect Programs, underscoring its market credibility and growth potential. The inclusion in both a major index and stock connect programs offered more liquidity. As of October 15, 2024, the company’s stock price has surged over 60% since its IPO on March 28, 2023, significantly outperforming the Hang Seng Composite Index during the same period[i]. In order to further optimize shareholder structure and enhance the Company’s trading liquidity, Domino’s Pizza LLC, an indirect wholly-owned subsidiary of Domino’s Pizza, recently announced an agreement to sell an aggregate of 10,000,000 of the Company’s shares, or 7.66% of its total issued share capital as of October 17, 2024, to purchasers including institutional investors through off-market block trades. Following this share sale, Domino’s Pizza LLC retains 6.21% of total issued share capital with a lock-up period of 90 days for its remaining shares. The enduring relationship between DPC Dash and DPZ remains robust. The allocation is an opportunity for DPC Dash to further improve liquidity and bring new dynamics to its shareholder structure. Notable international banks have rated DPC Dash as “Buy” or “Outperform”, showing confidence in the company’s fundamentals and stock performance.DPC Dash continues to demonstrate its market prowess with strategic growth, operational efficiency and customer satisfaction. The Company’s remarkable success can be largely attributed to its effective 4D strategy of Development, Delicious pizza at value, Delivery, and Digital. This comprehensive approach has enabled the company to serve high-quality, value-for-money pizzas to a steadily growing customer base. From 2021 to 2023, DPC Dash realized a Compounded Annual Growth Rate (CAGR) of 37.6% in revenue. In the first half of 2024, revenue reached RMB2.04 billion while both reported and adjusted net profit after tax turned positive for the first time.The Company’s “Go Deeper, Go Broader” strategy has been instrumental in its growth. As of September 30, 2024, DPC Dash operates 978 stores across 33 cities, reflecting a robust expansion with 210 new stores opened year-to-date. The combined total of net new stores added this year, stores currently under construction, and stores with signed agreements has reached approximately 100% of the full-year opening target for 2024. It is confident in maintaining this strong expansion dynamic, with plans to open its 1000th store in the fourth quarter of 2024 and open 300 to 350 new stores annually in 2025 and 2026. The store network expansion is supported by strong performance metrics, including holding 28 of the top 30 positions for first 30-day sales among Domino’s global network of over 21,000 stores as of the end of the third quarter of 2024. Since the current management took the helm in the third quarter of 2017, DPC Dash has since achieved 29 consecutive quarters of positive same-store sales growth (SSSG) despite market and industrial turbulence. Meanwhile, the company’s digital initiatives played a crucial role in driving customer engagement and loyalty. The company’s loyalty program boasted 21.7 million members as of September 2024, with 11 million new customers placing their first orders in the past 12 months with Domino’s Pizza China.Looking ahead, DPC Dash remains focused on its expansion plans and operational enhancements, aiming for sustainable, profitable growth in China’s vast pizza market through continual innovation and optimization. The company’s resilient business model and strategic initiatives position it well for continued success in this competitive industry. The company will continue to strengthen its market position and add value to consumers by constantly enhancing product quality, service level, and customer experience.[i] Based on closed stock price of DPC Dash and HSCI of March 28, 2023 and October 15, 2024. Copyright 2024 ACN Newswire via SeaPRwire.com.
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Kubur zaman Rom ditemui oleh pemilik rumah semasa projek pengubahsuaian ruang bawah tanah Berita

Kubur zaman Rom ditemui oleh pemilik rumah semasa projek pengubahsuaian ruang bawah tanah

(SeaPRwire) - Semasa musim sejuk 2023-2024, ahli arkeologi dari Pusat Penyelidikan Archeodunum telah dipanggil ke sebuah rumah yang terletak di sebuah selepas seorang pemilik rumah menemui rangka di ruang bawah tanahnya, mencetuskan penggalian selama berbulan-bulan yang penuh dengan penemuan penting.Kadang-kadang, penemuan purba datang apabila tidak dijangka, dan itu pasti berlaku bagi pemilik rumah yang menemui penemuan luar biasa itu tepat di rumahnya sendiri. Penemuan rangka tunggal oleh seorang pemilik rumah di Corbeil-Essonnes hanyalah permulaan penggalian arkeologi yang membawa kepada penemuan 38 pengebumian di seluruh empat bilik, menurut yang diterjemahkan Kehadiran tanah perkuburan dari Zaman Pertengahan telah diketahui kerana beberapa sarkofagus plaster dari zaman itu telah ditemui sebelum ini, menurut kenyataan itu, yang dipercayai oleh para sarjana berkaitan dengan kapel Notre-des-Champs. Kapel itu dipercayai telah dibina pada abad ke-7 di tapak kuil pagan, walaupun tidak ada bukti pembinaan yang dijumpai, menurut Archeodunum. Sebelum penggalian ini, tidak pernah disubjekkan kepada kajian saintifik, kenyataan itu juga menyatakan. Penggalian ini mendedahkan kubur yang jauh lebih tua daripada yang dijangkakan oleh ahli arkeologi, yang bermula dari abad ketiga Masihi hingga abad ke-10. Ia bukan sehingga awal Zaman Pertengahan bahawa amalan pengebumian mula berkembang. Pada masa ini, si mati kadang-kadang dihiasi, walaupun yang baru ditemui tidak, menurut Archeodunum. Selalunya, sisa-sisa lebih daripada satu diletakkan di dalam sarkofagus plaster, tetapi 10 yang dijumpai mengandungi sisa-sisa seorang individu sahaja di setiap satu. Sebelum ini, semasa zaman Rom, si mati diletakkan di atas belakang mereka di dalam kandang kayu.Analisis lanjut mengenai tanah perkuburan terus dilakukan, yang diharapkan oleh pakar akan membawa kepada penyelesaian persoalan yang tidak terjawab, seperti jantina, umur kematian dan keadaan hidup mereka yang jenazahnya digali, menurut Archeodunum. Selain itu, pakar akan berusaha mengelilingi objektif utama untuk memahami berapa ramai orang yang tinggal di kawasan itu semasa zaman purba dan Zaman Pertengahan, sambil juga memperoleh pemahaman yang lebih mendalam tentang bagaimana tradisi pengebumian berkembang dari masa ke masa, menurut sumber itu. Artikel ini disediakan oleh pembekal kandungan pihak ketiga. SeaPRwire (https://www.seaprwire.com/) tidak memberi sebarang waranti atau perwakilan berkaitan dengannya. Sektor: Top Story, Berita Harian SeaPRwire menyampaikan edaran siaran akhbar secara masa nyata untuk syarikat dan institusi, mencapai lebih daripada 6,500 kedai media, 86,000 penyunting dan wartawan, dan 3.5 juta desktop profesional di seluruh 90 negara. SeaPRwire menyokong pengedaran siaran akhbar dalam bahasa Inggeris, Korea, Jepun, Arab, Cina Ringkas, Cina Tradisional, Vietnam, Thai, Indonesia, Melayu, Jerman, Rusia, Perancis, Sepanyol, Portugis dan bahasa-bahasa lain.
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Pengebom AS Serang Kemudahan Senjata di Yaman yang Dikendalikan oleh Pasukan Houthi Berita

Pengebom AS Serang Kemudahan Senjata di Yaman yang Dikendalikan oleh Pasukan Houthi

(SeaPRwire) - Amerika Syarikat telah menyerang lima tapak ketenteraan yang dikawal oleh menggunakan pengebom B-2 untuk serangan tepat terhadap lokasi penyimpanan senjata."Pasukan AS menyasarkan beberapa kemudahan bawah tanah Houthis yang menempatkan pelbagai komponen senjata jenis yang digunakan oleh Houthis untuk menyasarkan awam dan di seluruh rantau ini," kata Setiausaha Pertahanan Lloyd J. Austin III dalam satu kenyataan. "Ini adalah demonstrasi unik keupayaan Amerika Syarikat untuk menyasarkan kemudahan yang ingin disembunyikan oleh musuh kita, tidak kira betapa dalamnya terkubur di bawah tanah, diperkukuh, atau dibentengi."Austin berkata penggunaan pengebom siluman jarak jauh B-2 Spirit Tentera Udara AS menunjukkan keupayaan serangan global AS untuk "mengambil tindakan terhadap sasaran ini apabila diperlukan, bila-bila masa, di mana-mana sahaja." "Selama lebih setahun, Houthis yang disokong Iran, Pengganas Global yang Ditentukan Khas, telah dengan sengaja dan secara haram menyerang kapal AS dan antarabangsa yang melalui Laut Merah, Selat Bab Al-Mandeb, dan Teluk Aden," katanya. Serangan haram Houthis terus mengganggu aliran perdagangan antarabangsa yang bebas, mengancam bencana alam sekitar, dan membahayakan nyawa orang awam yang tidak bersalah dan nyawa pasukan AS dan rakan kongsi, katanya. serangan itu diluluskan oleh Presiden Joe Biden."Atas arahan Presiden Biden, saya mengarahkan serangan yang disasarkan ini untuk terus merendahkan keupayaan Houthis untuk meneruskan tingkah laku yang tidak stabil dan untuk melindungi dan mempertahankan pasukan dan kakitangan AS di salah satu laluan air paling kritikal di dunia."Sekali lagi, Amerika Syarikat tidak akan teragak-agak untuk mengambil tindakan untuk mempertahankan nyawa dan aset Amerika; untuk menghalang serangan terhadap orang awam dan rakan kongsi serantau kami; dan untuk melindungi kebebasan navigasi dan meningkatkan keselamatan dan keselamatan di laluan air ini untuk kapal AS, gabungan, dan pedagang. "Kami akan terus menjelaskan kepada Houthis bahawa akan ada akibat untuk serangan mereka yang haram dan cuai. Saya bersyukur atas profesionalisme dan kemahiran pasukan Amerika yang berani yang mengambil bahagian dalam tindakan hari ini dan yang terus berjaga-jaga dalam mempertahankan Negara kita."Penilaian awal oleh Komando Pusat AS menunjukkan bahawa tiada serangan itu mencederakan mana-mana orang awam. Berikut adalah beberapa latar belakang mengenai kesan Houthis di Timur Tengah dan sepanjang koridor penghantaran di rantau ini:Artikel ini disediakan oleh pembekal kandungan pihak ketiga. SeaPRwire (https://www.seaprwire.com/) tidak memberi sebarang waranti atau perwakilan berkaitan dengannya. Sektor: Top Story, Berita Harian SeaPRwire menyampaikan edaran siaran akhbar secara masa nyata untuk syarikat dan institusi, mencapai lebih daripada 6,500 kedai media, 86,000 penyunting dan wartawan, dan 3.5 juta desktop profesional di seluruh 90 negara. SeaPRwire menyokong pengedaran siaran akhbar dalam bahasa Inggeris, Korea, Jepun, Arab, Cina Ringkas, Cina Tradisional, Vietnam, Thai, Indonesia, Melayu, Jerman, Rusia, Perancis, Sepanyol, Portugis dan bahasa-bahasa lain.
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A Joint Regional Cohort Study by Shimadzu, Eisai, Oita University, and Usuki City Medical Association JCN Newswire

A Joint Regional Cohort Study by Shimadzu, Eisai, Oita University, and Usuki City Medical Association

Shimadzu Corporation, Eisai Co., Ltd., Oita University, and Usuki City Medical Association have demonstrated the utility of blood biomarkers in predicting the accumulation of amyloid beta (Aβ)(1) in the brain, a noted cause of Alzheimer’s disease(2), in a cohort study conducted in Usuki City, Oita from November 2022. A research paper reporting the details of this study was published on October 10, 2024, in the journal Alzheimer’s & Dementia: Translational Research & Clinical Interventions.This joint research attempts to develop Japan’s first diagnostic workflow for mild cognitive impairment (MCI) due to Alzheimer’s disease and mild dementia based on blood biomarkers. Comprising a phase 1 and phase 2 study, the phase 1 study uses frozen samples of blood plasma from a regional cohort collected by a prospective cohort study performed in Usuki City between 2015 and 2019 to evaluate the utility of blood biomarkers in predicting Aβ accumulation in the brain. The phase 2 study is a prospective study that uses blood plasma samples collected from 100 newly recruited subjects through diagnostic workflows adopted at all levels of health care, from primary care physicians to specialists certified by dementia-related societies, to evaluate the psychological impact on participants of different results and who discloses them.The research paper primarily compiles results from the phase 1 study. The ability of blood biomarkers to predict the results of amyloid PET scans(3) was evaluated in terms of an area under the curve (AUC) value. Blood biomarker measurements performed by Shimadzu resulted in an AUC value of 0.94 and identified PET-positive patients in the regional cohort with a high degree of accuracy. The joint research also revealed the possibility to predict the progression of clinical symptoms using baseline blood biomarker results, i.e., the progression from MCI due to Alzheimer's disease to Alzheimer's dementia from analysis of participant data over a seven-year observation period. Blood biomarker testing is less invasive than amyloid PET and cerebrospinal fluid testing(4), and could reduce patient stress and help predict the future onset of dementia if used as an alternative to these two diagnostic methods. The data collection stage of phase 2 is complete with plans in place to carry out data analysis and draft an overall report of the results of both phases of the joint research.The four parties involved in this joint research are committed to building an ecosystem that improves the early diagnosis of Alzheimer’s through diagnostic workflows adopted at all levels of health care from primary care physicians to specialists who are members of dementia-related societies, and through this research develop social infrastructure that ensures patients and their families live happy and fulfilling lives.Comment by Noriyuki Kimura, an Associate Professor at the Department of Neurology, Faculty of Medicine, Oita UniversityTreatment of Alzheimer’s disease is approaching a new turning point with the emergence of anti-amyloid beta antibodies that will require the diagnosis of Alzheimer’s disease at the MCI or early dementia stage. Biomarker-based tests to detect amyloid accumulation in the brain include amyloid PET scans and cerebrospinal fluid testing, but PET scans are expensive and cerebrospinal fluid testing is highly invasive. Blood biomarker testing is low-cost and less invasive, and its adoption promises to reduce the financial and physical burden on patients.(1) Amyloid beta is a protein believed to cause Alzheimer’s disease that accumulates in the brain to form senile plaques beginning around 20 years before the onset of Alzheimer’s disease.(2) Alzheimer’s disease is the most common cause of dementia and its key pathological hallmarks are senile plaques, neurofibrillary tangles, and neuronal cell death.(3) Amyloid PET is a brain imaging test that can visualize amyloid beta accumulation in the brain.(4) Cerebrospinal fluid testing collects cerebrospinal fluid and tests it for amyloid-β 42, amyloid-β 40, phosphorylated tau protein, and total tau protein, which are biomarkers of Alzheimer’s disease.Research Paper InformationJournal name: Alzheimer's & Dementia: Translational Research & Clinical InterventionsTitle of paper: Plasma amyloid beta biomarkers predict amyloid positivity and longitudinal clinical progression in mild cognitive impairment.Authors: Takuya Ataka, Noriyuki Kimura, Naoki Kaneko, Teruaki Masuda, Yosuke Takeuchi, Kenichi Yabuuchi, Takeshi Mizukami, Tsukasa Takeuchi, Temmei Ito, Hideaki Tasai, Takehiko Miyagawa, Shunya Hanai, Shinichi Iwamoto, and Etsuro MatsubaraDOI: 10.1002/trc2.70008Related InformationNovember 22, 2022 Press releaseTo Develop Japan’s First Blood Biomarker-Based Diagnostic Workflow for DementiaShimadzu, Eisai, Oita University, and Usuki City Medical Association Commence Joint Researchwww.eisai.com/news/2022/news202280.html For Press and Media Inquiries, Please Contact:Shimadzu CorporationCorporate Communication Department Phone: +81-75-823-1110Eisai Co., Ltd.Public Relations Department Phone: +81-3-3817-5120Oita UniversityDepartment of Neurology, Faculty of Medicine Phone: +81-97-586-5814Usuki City Medical AssociationUsuki City Medical Association Office Phone: +81-972-63-0099 Copyright 2024 JCN Newswire via SeaPRwire.com.
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